OBJECTIVES: To investigate the prognostic value of median somatosensory evoked potentials (mSSEP) within the "therapeutic window" of ischemic stroke. MATERIALS AND METHODS: Twenty-two patients (mean age 60.8 +/- 14.8 years) with first ischemic stroke in middle cerebral artery territory without contraindications for thrombolysis underwent mSSEP investigation within 3 hours of onset. Stroke topography was verified within 48 hours by computed tomography. M-SSEP results (presence, amplitude and amplitude ratio, latency and central conduction time) were compared to severity of motor deficit at onset and to recovery at 6 months. RESULTS: M-SSEP were present in 17 patients, 7 of whom had partial and 10--complete motor recovery. Absence of mSSEP was found in 5 persons. None recovered function of the arm and only 2 were ambulatory at 6 months. CONCLUSIONS: In the earliest phase of ischemic stroke absence of mSSEP response is reliable predictor of poor functional outcome.
OBJECTIVES: To investigate the prognostic value of median somatosensory evoked potentials (mSSEP) within the "therapeutic window" of ischemic stroke. MATERIALS AND METHODS: Twenty-two patients (mean age 60.8 +/- 14.8 years) with first ischemic stroke in middle cerebral artery territory without contraindications for thrombolysis underwent mSSEP investigation within 3 hours of onset. Stroke topography was verified within 48 hours by computed tomography. M-SSEP results (presence, amplitude and amplitude ratio, latency and central conduction time) were compared to severity of motor deficit at onset and to recovery at 6 months. RESULTS: M-SSEP were present in 17 patients, 7 of whom had partial and 10--complete motor recovery. Absence of mSSEP was found in 5 persons. None recovered function of the arm and only 2 were ambulatory at 6 months. CONCLUSIONS: In the earliest phase of ischemic stroke absence of mSSEP response is reliable predictor of poor functional outcome.