Literature DB >> 1500357

Leualacin, a novel calcium blocker from Hapsidospora irregularis. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties.

K Hamano1, M Kinoshita, K Furuya, M Miyamoto, Y Takamatsu, A Hemmi, K Tanzawa.   

Abstract

A new calcium blocker, designated leualacin, has been isolated from Hapsidospora irregularis. The compound inhibits the binding of 3H-nitrendipine, a well known synthetic calcium blocker, to cardiac Ca channel in a competitive manner, although its structure is completely different from dihydropyridines.

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Year:  1992        PMID： 1500357     DOI： 10.7164/antibiotics.45.899

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  3 in total

1.  Three new fusidic acid derivatives and their antibacterial activity.

Authors:  Shuwei Zhang; Siyuan Wang; Qian Zhang; Cheng-Wei Tom Chang; Jixun Zhan
Journal:  Bioorg Med Chem Lett       Date:  2015-03-20       Impact factor: 2.823

2.  Identification of Cyclic Depsipeptides and Their Dedicated Synthetase from Hapsidospora irregularis.

Authors:  Shuwei Zhang; Yixing Qiu; Thomas B Kakule; Zhenyu Lu; Fuchao Xu; John G Lamb; Christopher A Reilly; Yong Zheng; Shing Wo Simon Sham; Wei Wang; Lijiang Xuan; Eric W Schmidt; Jixun Zhan
Journal:  J Nat Prod       Date:  2017-01-20       Impact factor: 4.050

Review 3.  Structural Diversity and Biological Activities of Cyclic Depsipeptides from Fungi.

Authors:  Xiaohan Wang; Xiao Gong; Peng Li; Daowan Lai; Ligang Zhou
Journal:  Molecules       Date:  2018-01-15       Impact factor: 4.411
  3 in total

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