Literature DB >> 15003224

Target-based discovery of novel herbicides.

Wolfgang Lein1, Frederik Börnke, Andreas Reindl, Thomas Ehrhardt, Mark Stitt, Uwe Sonnewald.   

Abstract

In the past 10 years, strategies for the first steps of herbicide discovery have switched from the testing of chemicals for efficacy on whole plants towards the use of in-vitro assays against molecular targets. Many different approaches have been developed to identify bona fide targets for in-vitro screening. Developments in functional genomics and in pharmaceutical research could aid the development of assay systems for the evaluation of chemicals for their suitability as lead structures in herbicide discovery.

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Year:  2004        PMID： 15003224     DOI： 10.1016/j.pbi.2004.01.001

Source DB:  PubMed          Journal:  Curr Opin Plant Biol        ISSN： 1369-5266            Impact factor:   7.834


  6 in total

1.  Screening marine fungi for inhibitors of the C4 plant enzyme pyruvate phosphate dikinase: unguinol as a potential novel herbicide candidate.

Authors:  Cherie A Motti; David G Bourne; James N Burnell; Jason R Doyle; Dianne S Haines; Catherine H Liptrot; Lyndon E Llewellyn; Shilo Ludke; Andrew Muirhead; Dianne M Tapiolas
Journal:  Appl Environ Microbiol       Date:  2007-01-12       Impact factor: 4.792

2.  Herbicides as weed control agents: state of the art: II. Recent achievements.

Authors:  Hansjoerg Kraehmer; Andreas van Almsick; Roland Beffa; Hansjoerg Dietrich; Peter Eckes; Erwin Hacker; Ruediger Hain; Harry John Strek; Hermann Stuebler; Lothar Willms
Journal:  Plant Physiol       Date:  2014-08-07       Impact factor: 8.340

3.  A Robot-based platform to measure multiple enzyme activities in Arabidopsis using a set of cycling assays: comparison of changes of enzyme activities and transcript levels during diurnal cycles and in prolonged darkness.

Authors:  Yves Gibon; Oliver E Blaesing; Jan Hannemann; Petronia Carillo; Melanie Höhne; Janneke H M Hendriks; Natalia Palacios; Joanna Cross; Joachim Selbig; Mark Stitt
Journal:  Plant Cell       Date:  2004-11-17       Impact factor: 11.277

4.  Design, Synthesis, and Biological Activities of Novel 1,3,5-Trimethylpyrazole-Containing Malonamide Derivatives.

Authors:  Qi-Bo Li; Min Liao; Qing Liu; Tong Feng; Zhi-Yuan Xu; Chang-Hui Rui; Shang-Zhong Liu
Journal:  Molecules       Date:  2019-02-03       Impact factor: 4.411

5.  Efficient In Vivo Screening Method for the Identification of C4 Photosynthesis Inhibitors Based on Cell Suspensions of the Single-Cell C4 Plant Bienertia sinuspersici.

Authors:  Alexander Minges; Dominik Janßen; Sascha Offermann; Georg Groth
Journal:  Front Plant Sci       Date:  2019-10-30       Impact factor: 5.753

6.  Temporally resolved GC-MS-based metabolic profiling of herbicide treated plants treated reveals that changes in polar primary metabolites alone can distinguish herbicides of differing mode of action.

Authors:  Sandra Trenkamp; Peter Eckes; Marco Busch; Alisdair R Fernie
Journal:  Metabolomics       Date:  2008-12-13       Impact factor: 4.290
  6 in total

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