Literature DB >> 15002887

Effect of triclosan on healing following non-surgical periodontal therapy in smokers.

Varunee Kerdvongbundit1, Ulf M E Wikesjö.   

Abstract

BACKGROUND: Tobacco smoking is an established risk factor for periodontitis, and is associated with periodontal attachment and tooth loss. Clinical studies have indicated that smoking may adversely affect and impede healing following periodontal therapy. Adjunctive antimicrobials, on the other hand, have been shown to enhance the effect of non-surgical periodontal therapy. The objective of this study was to evaluate the effect of a triclosan/copolymer/fluoride dentifrice on healing following non-surgical periodontal therapy in smokers.
METHODS: Sixty smokers (aged 35-59 years; 23 females) with chronic periodontal disease volunteered to participate in a double-blind, randomized, controlled, clinical trial. The subjects were randomly assigned to use a triclosan/copolymer/fluoride (30 subjects) or a standard fluoride (30 subjects) dentifrice and received detailed information on proper techniques for self-performed plaque control. The participants then received non-surgical periodontal therapy followed by periodontal maintenance care every 6 months over 24 months. Clinical recordings included evaluation of oral hygiene standards, gingival health, and periodontal status.
RESULTS: Subjects using the triclosan/copolymer/fluoride dentifrice exhibited significantly improved oral hygiene conditions, gingival health, and periodontal status compared with those using the standard fluoride dentifrice over the 24-month maintenance interval.
CONCLUSIONS: The results suggest that an oral hygiene regimen including a triclosan/copolymer/fluoride dentifrice may sustain the short-term effect of non-surgical periodontal therapy in smokers.

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Year:  2003        PMID: 15002887     DOI: 10.1046/j.0303-6979.2003.00417.x

Source DB:  PubMed          Journal:  J Clin Periodontol        ISSN: 0303-6979            Impact factor:   8.728


  3 in total

1.  Triclosan alters antimicrobial and inflammatory responses of epithelial cells.

Authors:  M A Wallet; N l Calderon; T R Alonso; C S Choe; D l Catalfamo; C J Lalane; K G Neiva; F Panagakos; S M Wallet
Journal:  Oral Dis       Date:  2013-04       Impact factor: 3.511

Review 2.  Triclosan: A Small Molecule with Controversial Roles.

Authors:  Maria Stefania Sinicropi; Domenico Iacopetta; Jessica Ceramella; Alessia Catalano; Annaluisa Mariconda; Michele Pellegrino; Carmela Saturnino; Pasquale Longo; Stefano Aquaro
Journal:  Antibiotics (Basel)       Date:  2022-05-30

3.  Adjunctive use of modified Yunu-Jian in the non-surgical treatment of male smokers with chronic periodontitis: a randomized double-blind, placebo-controlled clinical trial.

Authors:  Kwan-Yat Zee; Pui Sze Chan; Johnson Chun Sing Ho; Stanley Man Lung Lai; Esmonde Francis Corbet; Wai Keung Leung
Journal:  Chin Med       Date:  2016-09-20       Impact factor: 5.455

  3 in total

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