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Literature DB >> 15001956

The development of hepatocellular carcinoma among prospectively followed children with chronic hepatitis B virus infection.

Wan-Hsin Wen¹, Mei-Hwei Chang, Hong-Yuan Hsu, Yen-Hsuan Ni, Huey-Ling Chen.

Abstract

We prospectively followed 426 children with chronic hepatitis B virus infection. During 6250 person-years, 2 boys developed hepatocellular carcinoma, with an incidence of 32 per 100,000 person-years. Both had e antigen seroconversion in early childhood and cirrhosis. Early e antigen seroconversion and/or cirrhosis may be risk factors for hepatocellular carcinoma.

Entities: Disease Species

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Year: 2004 PMID： 15001956 DOI： 10.1016/j.jpeds.2003.11.022

Source DB: PubMed Journal: J Pediatr ISSN： 0022-3476 Impact factor: 4.406

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Cited

18 in total

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