Literature DB >> 15000516

Calcium channels: unanswered questions.

Stephen W Jones1.   

Abstract

Despite decades of intensive research, many questions remain unresolved regarding the structure and function of voltage-dependent calcium channels. This review considers some of those questions: Where is the activation gate? Where are the inactivation gates? How are the voltage sensors coupled to the gates? Are bacterial K+ channels good models for the Ca2+ channel pore? Are protein-protein interactions fundamental to Ca2+ channel function? Do voltage-dependent Ca2+ channels regulate basal intracellular Ca2+? Are N and P/Q channels specialized for fast neurotransmitter release?

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Year:  2003        PMID： 15000516     DOI： 10.1023/b:jobb.0000008020.86004.28

Source DB:  PubMed          Journal:  J Bioenerg Biomembr        ISSN： 0145-479X            Impact factor:   2.945


  133 in total

1.  A family of gamma-like calcium channel subunits.

Authors:  N Klugbauer; S Dai; V Specht; L Lacinová; E Marais; G Bohn; F Hofmann
Journal:  FEBS Lett       Date:  2000-03-24       Impact factor: 4.124

2.  Nomenclature of voltage-gated calcium channels.

Authors:  E A Ertel; K P Campbell; M M Harpold; F Hofmann; Y Mori; E Perez-Reyes; A Schwartz; T P Snutch; T Tanabe; L Birnbaumer; R W Tsien; W A Catterall
Journal:  Neuron       Date:  2000-03       Impact factor: 17.173

Review 3.  The TRP channels, a remarkably functional family.

Authors:  Craig Montell; Lutz Birnbaumer; Veit Flockerzi
Journal:  Cell       Date:  2002-03-08       Impact factor: 41.582

4.  A Xenopus oocyte beta subunit: evidence for a role in the assembly/expression of voltage-gated calcium channels that is separate from its role as a regulatory subunit.

Authors:  E Tareilus; M Roux; N Qin; R Olcese; J Zhou; E Stefani; L Birnbaumer
Journal:  Proc Natl Acad Sci U S A       Date:  1997-03-04       Impact factor: 11.205

5.  Identification of a syntaxin-binding site on N-type calcium channels.

Authors:  Z H Sheng; J Rettig; M Takahashi; W A Catterall
Journal:  Neuron       Date:  1994-12       Impact factor: 17.173

6.  Presynaptic calcium currents in squid giant synapse.

Authors:  R Llinás; I Z Steinberg; K Walton
Journal:  Biophys J       Date:  1981-03       Impact factor: 4.033

7.  Neuronal Ca(V)1.3alpha(1) L-type channels activate at relatively hyperpolarized membrane potentials and are incompletely inhibited by dihydropyridines.

Authors:  W Xu; D Lipscombe
Journal:  J Neurosci       Date:  2001-08-15       Impact factor: 6.167

8.  Ca2+ currents in cerebral artery smooth muscle cells of rat at physiological Ca2+ concentrations.

Authors:  M Rubart; J B Patlak; M T Nelson
Journal:  J Gen Physiol       Date:  1996-04       Impact factor: 4.086

Review 9.  Ca2+ channels as targets of neurological disease: Lambert-Eaton Syndrome and other Ca2+ channelopathies.

Authors:  Michael T Flink; William D Atchison
Journal:  J Bioenerg Biomembr       Date:  2003-12       Impact factor: 2.945

10.  Calcium currents in the A7r5 smooth muscle-derived cell line. Increase in current and selective removal of voltage-dependent inactivation by intracellular trypsin.

Authors:  C A Obejero-Paz; S W Jones; A Scarpa
Journal:  J Gen Physiol       Date:  1991-12       Impact factor: 4.086
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  12 in total

Review 1.  The ß subunit of voltage-gated Ca2+ channels.

Authors:  Zafir Buraei; Jian Yang
Journal:  Physiol Rev       Date:  2010-10       Impact factor: 37.312

2.  Influence of Ca2+-binding proteins and the cytoskeleton on Ca2+-dependent inactivation of high-voltage activated Ca2+ currents in thalamocortical relay neurons.

Authors:  Sven G Meuth; Tatjana Kanyshkova; Peter Landgraf; Hans-Christian Pape; Thomas Budde
Journal:  Pflugers Arch       Date:  2005-01-13       Impact factor: 3.657

3.  Spike propagation in dendrites with stochastic ion channels.

Authors:  Kamran Diba; Christof Koch; Idan Segev
Journal:  J Comput Neurosci       Date:  2006-02-20       Impact factor: 1.621

Review 4.  A short history of voltage-gated calcium channels.

Authors:  Annette C Dolphin
Journal:  Br J Pharmacol       Date:  2006-01       Impact factor: 8.739

Review 5.  Ca(2+) signaling by T-type Ca(2+) channels in neurons.

Authors:  Lucius Cueni; Marco Canepari; John P Adelman; Anita Lüthi
Journal:  Pflugers Arch       Date:  2008-09-11       Impact factor: 3.657

6.  Synaptic control of the shape of the motoneuron pool input-output function.

Authors:  Randall K Powers; Charles J Heckman
Journal:  J Neurophysiol       Date:  2017-01-04       Impact factor: 2.714

7.  Contribution of electromechanical coupling between Kv and Ca v1.2 channels to coronary dysfunction in obesity.

Authors:  Zachary C Berwick; Gregory M Dick; Heather A O'Leary; Shawn B Bender; Adam G Goodwill; Steven P Moberly; Meredith Kohr Owen; Steven J Miller; Alexander G Obukhov; Johnathan D Tune
Journal:  Basic Res Cardiol       Date:  2013-07-16       Impact factor: 17.165

8.  Y3+ block demonstrates an intracellular activation gate for the alpha1G T-type Ca2+ channel.

Authors:  Carlos A Obejero-Paz; I Patrick Gray; Stephen W Jones
Journal:  J Gen Physiol       Date:  2004-12       Impact factor: 4.086

9.  Permeation and gating in CaV3.1 (alpha1G) T-type calcium channels effects of Ca2+, Ba2+, Mg2+, and Na+.

Authors:  Nilofar Khan; I Patrick Gray; Carlos A Obejero-Paz; Stephen W Jones
Journal:  J Gen Physiol       Date:  2008-08       Impact factor: 4.086

10.  Regulation of glutamatergic and GABAergic neurotransmission in the chick nucleus laminaris: role of N-type calcium channels.

Authors:  Y Lu
Journal:  Neuroscience       Date:  2009-09-12       Impact factor: 3.590
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