Literature DB >> 14999384

[Chronic inflammatory bowel diseases competence network ].

U R Fölsch1, J Grebe, S Schreiber.   

Abstract

Inflammatory bowel diseases (IBD) are intermittently appearing, often chronic diseases mostly affecting young people between 20-30 years of age influencing their quality of life and socioeconomic efficiency. The triggering factors for the development of IBD are not completely understood: besides environmental factors there is clear evidence for additional genetic factors influencing the risk of disease and the pattern of gut inflammation in Crohn's disease. Pathopysiological discoveries are leading to new therapeutic opportunities which are conducted in large clinical studies with main participation of the competence network IBD. The disseminated structure of the network comprising universitary and nonuniversitary hospitals and labs, the self-help-organization DCCV and its vertical cooperation with general practitioners nationwide gives opportunity to describe the diseases from the point of view of the scientist and the physician simultaneously. Therefore the competence network IBD yields the basis for the standardized integration of patient information, for the development of guidelines and the establishment of a quality management system thus leading to an improvement of scientific and clinical research.

Entities:  

Mesh:

Year:  2004        PMID: 14999384     DOI: 10.1007/s00108-004-1158-y

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  12 in total

1.  [Measuring quality of life in gastroenterology--concepts, instruments and problems].

Authors:  W Häuser; D Grandt
Journal:  Z Gastroenterol       Date:  2001-06       Impact factor: 2.000

Review 2.  [Diagnostics and treatment of Crohn's disease -- results of an evidence-based consensus conference of the German Society for Digestive and Metabolic Diseases].

Authors:  E F Stange; S Schreiber; U R Fölsch; A von Herbay; J Schölmerich; J Hoffmann; M Zeitz; W E Fleig; H J Buhr; A J Kroesen; G Moser; H Matthes; G Adler; M Reinshagen; J Stein
Journal:  Z Gastroenterol       Date:  2003-01       Impact factor: 2.000

3.  Role of T lymphocytes in rat 2,4,6-trinitrobenzene sulphonic acid (TNBS) induced colitis: increased mortality after gammadelta T cell depletion and no effect of alphabeta T cell depletion.

Authors:  J C Hoffmann; K Peters; S Henschke; B Herrmann; K Pfister; J Westermann; M Zeitz
Journal:  Gut       Date:  2001-04       Impact factor: 23.059

4.  Ulcerative colitis and Crohn's disease in an unselected population of monozygotic and dizygotic twins. A study of heritability and the influence of smoking.

Authors:  C Tysk; E Lindberg; G Järnerot; B Flodérus-Myrhed
Journal:  Gut       Date:  1988-07       Impact factor: 23.059

5.  [Measurement of outpatient treatment costs of chronic inflammatory bowel diseases at a German university hospital].

Authors:  Margrit Rösch; Reiner Leidl; Stefanie Thomas; Christian von Tirpitz; Max Reinshagen; Guido Adler; Hans-Helmut König
Journal:  Med Klin (Munich)       Date:  2002-03-15

6.  Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease.

Authors:  J P Hugot; M Chamaillard; H Zouali; S Lesage; J P Cézard; J Belaiche; S Almer; C Tysk; C A O'Morain; M Gassull; V Binder; Y Finkel; A Cortot; R Modigliani; P Laurent-Puig; C Gower-Rousseau; J Macry; J F Colombel; M Sahbatou; G Thomas
Journal:  Nature       Date:  2001-05-31       Impact factor: 49.962

7.  [Cost measurement based on a cost diary in patients with inflammatory bowel disease].

Authors:  M Rösch; R Leidl; C von Tirpitz; M Reinshagen; G Adler; H H König
Journal:  Z Gastroenterol       Date:  2002-04       Impact factor: 2.000

8.  Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: a cohort study.

Authors:  Jochen Hampe; Jochen Grebe; Susanna Nikolaus; Camilla Solberg; Peter J P Croucher; Silvia Mascheretti; Jörgen Jahnsen; Björn Moum; Bodo Klump; Michael Krawczak; Muddassar M Mirza; Ulrich R Foelsch; Morten Vatn; Stefan Schreiber
Journal:  Lancet       Date:  2002-05-11       Impact factor: 79.321

9.  Effects of the anti-CD2 mAb OX34 on in vivo proliferation.

Authors:  J C Hoffmann; C Herklotz; M Zeitz; B Bayer; H Zeidler; J Westermann
Journal:  Ann N Y Acad Sci       Date:  1998-11-17       Impact factor: 5.691

10.  Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations.

Authors:  J Hampe; A Cuthbert; P J Croucher; M M Mirza; S Mascheretti; S Fisher; H Frenzel; K King; A Hasselmeyer; A J MacPherson; S Bridger; S van Deventer; A Forbes; S Nikolaus; J E Lennard-Jones; U R Foelsch; M Krawczak; C Lewis; S Schreiber; C G Mathew
Journal:  Lancet       Date:  2001-06-16       Impact factor: 79.321

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