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Literature DB >> 14999154

Rho-regulatory proteins in breast cancer cell motility and invasion.

Abstract

The importance of the Rho-GTPases in cancer progression, particularly in the area of metastasis, is becoming increasingly evident. This review will provide an overview of the role of the Rho-regulatory proteins in breast cancer metastatis.

Entities: Disease

Mesh：

Substances：

Year: 2004 PMID： 14999154 DOI： 10.1023/B:BREA.0000018424.43445.f3

Source DB: PubMed Journal: Breast Cancer Res Treat ISSN： 0167-6806 Impact factor: 4.872

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Cited

27 in total

Review 1. Role of mTOR signaling in tumor cell motility, invasion and metastasis.

Authors: Hongyu Zhou; Shile Huang
Journal: Curr Protein Pept Sci Date: 2011-02 Impact factor: 3.272

Review 2. Metastasis suppressor proteins: discovery, molecular mechanisms, and clinical application.

Authors: Carrie W Rinker-Schaeffer; James P O'Keefe; Danny R Welch; Dan Theodorescu
Journal: Clin Cancer Res Date: 2006-07-01 Impact factor: 12.531

3. Estrogen and resveratrol regulate Rac and Cdc42 signaling to the actin cytoskeleton of metastatic breast cancer cells.

Authors: Nicolas G Azios; Lakshmi Krishnamoorthy; Micheleen Harris; Luis A Cubano; Michael Cammer; Surangani F Dharmawardhane
Journal: Neoplasia Date: 2007-02 Impact factor: 5.715

4. Characterization of EHop-016, novel small molecule inhibitor of Rac GTPase.

Authors: Brenda L Montalvo-Ortiz; Linette Castillo-Pichardo; Eliud Hernández; Tessa Humphries-Bickley; Alina De la Mota-Peynado; Luis A Cubano; Cornelis P Vlaar; Suranganie Dharmawardhane
Journal: J Biol Chem Date: 2012-03-01 Impact factor: 5.157

5. Loss of Rho GDIα and resistance to tamoxifen via effects on estrogen receptor α.

Authors: Ines Barone; Lauren Brusco; Guowei Gu; Jennifer Selever; Amanda Beyer; Kyle R Covington; Anna Tsimelzon; Tao Wang; Susan G Hilsenbeck; Gary C Chamness; Sebastiano Andò; Suzanne A W Fuqua
Journal: J Natl Cancer Inst Date: 2011-03-29 Impact factor: 13.506

10. Cytoplasmic ACK1 interaction with multiple receptor tyrosine kinases is mediated by Grb2: an analysis of ACK1 effects on Axl signaling.

Authors: Lin Pao-Chun; Perry M Chan; Wing Chan; Ed Manser
Journal: J Biol Chem Date: 2009-10-08 Impact factor: 5.157

Rho-regulatory proteins in breast cancer cell motility and invasion.

Review 1. Role of mTOR signaling in tumor cell motility, invasion and metastasis.

Review 2. Metastasis suppressor proteins: discovery, molecular mechanisms, and clinical application.

3. Estrogen and resveratrol regulate Rac and Cdc42 signaling to the actin cytoskeleton of metastatic breast cancer cells.

4. Characterization of EHop-016, novel small molecule inhibitor of Rac GTPase.

5. Loss of Rho GDIα and resistance to tamoxifen via effects on estrogen receptor α.

Review 6. Pleiotropic functions of Rho GTPase signaling: a Trojan horse or Achilles' heel for breast cancer treatment?

7. High-frequency promoter hypermethylation of the deleted in liver cancer-1 gene in multiple myeloma.

8. PLC-gamma1 and Rac1 coregulate EGF-induced cytoskeleton remodeling and cell migration.

9. Role of isoprenylcysteine carboxylmethyltransferase-catalyzed methylation in Rho function and migration.

10. Cytoplasmic ACK1 interaction with multiple receptor tyrosine kinases is mediated by Grb2: an analysis of ACK1 effects on Axl signaling.