Literature DB >> 14998486

Ezrin...a metastatic detERMinant?

Marcello Curto1, Andrea I McClatchey.   

Abstract

The insidious process of tumor metastasis is the most devastating and least well-understood aspect of cancer. Metastasis is very complex and employs many cellular processes, suggesting that individual metastatic determinants may not be easily identified. Mounting evidence, culminating in the work described in two recent articles, strongly suggests that the membrane:cytoskeleton organizer Ezrin can promote tumor metastasis. Ultimately, a better understanding of exactly how Ezrin confers metastatic advantage will provide important insight into this key problem in cancer biology.

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Year:  2004        PMID： 14998486     DOI： 10.1016/s1535-6108(04)00031-5

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  41 in total

1.  Fas-associated death domain (FADD) and the E3 ubiquitin-protein ligase TRIM21 interact to negatively regulate virus-induced interferon production.

Authors:  Jennifer A Young; Decha Sermwittayawong; Hee-Jung Kim; Suruchi Nandu; Namsil An; Hediye Erdjument-Bromage; Paul Tempst; Laurent Coscoy; Astar Winoto
Journal:  J Biol Chem       Date:  2010-12-23       Impact factor: 5.157

2.  Proteomics analysis of the ezrin interactome in B cells reveals a novel association with Myo18aα.

Authors:  Ken Matsui; Neetha Parameswaran; Nayer Bagheri; Belinda Willard; Neetu Gupta
Journal:  J Proteome Res       Date:  2011-07-28       Impact factor: 4.466

3.  Increase in ezrin expression from benign to malignant breast tumours.

Authors:  Daphne Gschwantler-Kaulich; Camilla Natter; Stefan Steurer; Ingrid Walter; Almut Thomas; Mohamed Salama; Christian F Singer
Journal:  Cell Oncol (Dordr)       Date:  2013-10-16       Impact factor: 6.730

4.  Malignant fibrous histiocytoma of visceral organs: clinicopathologic features and diagnostic value of ezrin and HMG-CoA reductase.

Authors:  Jinyang Gu; Shu Zhang; Xingyu Wu; Jiong Shi; Bin Zhang; Xiaoqi Zhang; Jun Yang; Halmurat Obulkasim; Fei Duan; Chao Deng; Jing He; Xiaoping Zou; Yitao Ding
Journal:  Int J Clin Exp Pathol       Date:  2015-03-01

5.  p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice.

Authors:  Whitney G Smalley-Freed; Andrey Efimov; Patrick E Burnett; Sarah P Short; Michael A Davis; Deborah L Gumucio; M Kay Washington; Robert J Coffey; Albert B Reynolds
Journal:  J Clin Invest       Date:  2010-05-17       Impact factor: 14.808

6.  THE RETINOBLASTOMA PROTEIN: A MASTER TUMOR SUPPRESSOR ACTS AS A LINK BETWEEN CELL CYCLE AND CELL ADHESION.

Authors:  B E Engel; W D Cress; P G Santiago-Cardona
Journal:  Cell Health Cytoskelet       Date:  2014-12-18

Review 7.  Osteosarcoma metastasis: prospective role of ezrin.

Authors:  Yuanjin Zhang; Ling Zhang; Guofu Zhang; Songbai Li; Jun Duan; Jie Cheng; Guozhen Ding; Chibing Zhou; Jie Zhang; Pengcheng Luo; Dongbing Cai; Lianghong Kuang; Yichun Zhou; Liqun Tong; Xiangdong Yu; Lifang Zhang; Lijun Xu; Li Yu; Xiaomei Shi; Aihong Ke
Journal:  Tumour Biol       Date:  2014-03-09

8.  Ezrin tunes the magnitude of humoral immunity.

Authors:  Debasis Pore; Neetha Parameswaran; Ken Matsui; Matthew B Stone; Ichiko Saotome; Andrea I McClatchey; Sarah L Veatch; Neetu Gupta
Journal:  J Immunol       Date:  2013-09-16       Impact factor: 5.422

Review 9.  The role of palladin in actin organization and cell motility.

Authors:  Silvia M Goicoechea; Daniel Arneman; Carol A Otey
Journal:  Eur J Cell Biol       Date:  2008-03-14       Impact factor: 4.492

10.  Epigenetic drugs can stimulate metastasis through enhanced expression of the pro-metastatic Ezrin gene.

Authors:  Yanlin Yu; Pingyao Zeng; Jingbo Xiong; Ziyang Liu; Shelley L Berger; Glenn Merlino
Journal:  PLoS One       Date:  2010-09-13       Impact factor: 3.240
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