Literature DB >> 14997311

["Tingling feet," forgetfulness, and progressive personality changes in a 63-year-old patient].

T Karrasch1, M Weil, R Voltz, C Schulz, F Audebert, M Woenckhaus, F Hofstädter, U Bogdahn, J Schölmerich, A Schäffler, A Steinbrecher.   

Abstract

A 63-year-old female was admitted to the hospital with leg and forearm paresthesias. We found progressive ataxia, dementia, and psychosocial deterioration. The clinical symptoms, the neurologic and psychiatric abnormalities together with the inflammatory cerebrospinal fluid alteration and the cerebral magnetic resonance imaging changes suggested a paraneoplastic etiology. It was confirmed by paraneoplastic antineuronal antibodies in the patient's serum and the histological diagnosis of a small cell bronchial carcinoma. The prognosis of patients with paraneoplastic symptoms is the better the earlier a diagnosis is established and antitumor therapy is initiated.

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Mesh:

Year:  2004        PMID: 14997311     DOI: 10.1007/s00108-003-1115-1

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  9 in total

1.  Anti-Hu-associated paraneoplastic encephalomyelitis: analysis of 200 patients.

Authors:  F Graus; F Keime-Guibert; R Reñe; B Benyahia; T Ribalta; C Ascaso; G Escaramis; J Y Delattre
Journal:  Brain       Date:  2001-06       Impact factor: 13.501

2.  Primary sensory neuropathy with muscular changes associated with carcinoma.

Authors:  D DENNY-BROWN
Journal:  J Neurol Neurosurg Psychiatry       Date:  1948-05       Impact factor: 10.154

3.  Autoimmunity in paraneoplastic neurological syndromes: closer to the truth?

Authors:  K A Jaeckle
Journal:  Ann Neurol       Date:  1999-02       Impact factor: 10.422

Review 4.  Autoimmune central nervous system paraneoplastic disorders: mechanisms, diagnosis, and therapeutic options.

Authors:  E J Dropcho
Journal:  Ann Neurol       Date:  1995-05       Impact factor: 10.422

5.  Neuronal antinuclear antibody in sensory neuronopathy from lung cancer.

Authors:  F Graus; C Cordon-Cardo; J B Posner
Journal:  Neurology       Date:  1985-04       Impact factor: 9.910

6.  Diagnostic value of anti-neuronal antibodies for paraneoplastic disorders of the nervous system.

Authors:  J W Moll; S C Henzen-Logmans; T A Splinter; M E van der Burg; C J Vecht
Journal:  J Neurol Neurosurg Psychiatry       Date:  1990-11       Impact factor: 10.154

Review 7.  Paraneoplastic syndromes associated with anti-Hu antibodies.

Authors:  H Senties-Madrid; F Vega-Boada
Journal:  Isr Med Assoc J       Date:  2001-02       Impact factor: 0.892

8.  Paraneoplastic limbic encephalitis: neurological symptoms, immunological findings and tumour association in 50 patients.

Authors:  S H Gultekin; M R Rosenfeld; R Voltz; J Eichen; J B Posner; J Dalmau
Journal:  Brain       Date:  2000-07       Impact factor: 13.501

Review 9.  Paraneoplastic neurological syndromes: an update on diagnosis, pathogenesis, and therapy.

Authors:  Raymond Voltz
Journal:  Lancet Neurol       Date:  2002-09       Impact factor: 44.182

  9 in total

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