Literature DB >> 14996634

The effectiveness of secretin in the management of autism.

Janet K Kern1, Elvira Espinoza, Madhukar H Trivedi.   

Abstract

Autism is a complex neurological disorder that severely impacts a child's ability to communicate and interact socially. Many treatments have attempted to alleviate the symptoms of autism, but with limited success. After reports of improvements in autistic children who received secretin, this hormone became popular as a possible treatment for autism. Since then, the interest in secretin has greatly increased, as well as the demand for secretin by parents of autistic children. However, there is still limited experimental evidence that supports its effectiveness. Many biological studies and clinical trials were conducted to test the effectiveness of secretin in treating autism. This review discusses the autistic disorder, instruments used in the trials, and reports the findings of some of these studies.

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Year:  2004        PMID: 14996634     DOI: 10.1517/14656566.5.2.379

Source DB:  PubMed          Journal:  Expert Opin Pharmacother        ISSN: 1465-6566            Impact factor:   3.889


  6 in total

Review 1.  Emerging drugs for the treatment of symptoms associated with autism spectrum disorders.

Authors:  Logan K Wink; Martin H Plawecki; Craig A Erickson; Kimberly A Stigler; Christopher J McDougle
Journal:  Expert Opin Emerg Drugs       Date:  2010-09       Impact factor: 4.191

Review 2.  Chemical modification of class II G protein-coupled receptor ligands: frontiers in the development of peptide analogs as neuroendocrine pharmacological therapies.

Authors:  Megan C Chapter; Caitlin M White; Angela DeRidder; Wayne Chadwick; Bronwen Martin; Stuart Maudsley
Journal:  Pharmacol Ther       Date:  2009-08-15       Impact factor: 12.310

3.  Brain effects of chronic IBD in areas abnormal in autism and treatment by single neuropeptides secretin and oxytocin.

Authors:  Martha G Welch; Thomas B Welch-Horan; Muhammad Anwar; Nargis Anwar; Robert J Ludwig; David A Ruggiero
Journal:  J Mol Neurosci       Date:  2005       Impact factor: 3.444

4.  Treatments for autism: parental choices and perceptions of change.

Authors:  Anne Bowker; Nadia M D'Angelo; Robin Hicks; Kerry Wells
Journal:  J Autism Dev Disord       Date:  2011-10

5.  Short report: Autistic gastrointestinal and eating symptoms treated with secretin: a subtype of autism.

Authors:  Stefano Pallanti; Stefano Lassi; Giampaolo La Malfa; Marco Campigli; Roberto Di Rubbo; Giulia Paolini; Valentina Cesarali
Journal:  Clin Pract Epidemiol Ment Health       Date:  2005-11-15

Review 6.  Is sleep essential for neural plasticity in humans, and how does it affect motor and cognitive recovery?

Authors:  Maurizio Gorgoni; Aurora D'Atri; Giulia Lauri; Paolo Maria Rossini; Fabio Ferlazzo; Luigi De Gennaro
Journal:  Neural Plast       Date:  2013-06-11       Impact factor: 3.599

  6 in total

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