Literature DB >> 14996499

Bcl-2 proteins: master switches at the intersection of death signaling and the survival control by Raf kinases.

Ulf R Rapp1, Ulrike Rennefahrt, Jakob Troppmair.   

Abstract

Bcl-2 family members are central to the control of cell survival. Work of the last years has established that the function of these proteins can be regulated by mitogenic signaling cascades. Within the scope of this review, we will discuss the contribution of Bcl-2-dependent signaling pathways to cell survival by Raf kinases and also address the underlying mechanisms.

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Year:  2004        PMID： 14996499     DOI： 10.1016/j.bbamcr.2003.10.015

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  8 in total

1.  Granulocyte macrophage colony-stimulating factor shows anti-apoptotic activity via the PI3K-NF-κB-HIF-1α-survivin pathway in mouse neural progenitor cells.

Authors:  Jung Kyoung Choi; Kil Hwan Kim; So Ra Park; Byung Hyune Choi
Journal:  Mol Neurobiol       Date:  2013-09-11       Impact factor: 5.590

2.  Cortical migration defects in mice expressing A-RAF from the B-RAF locus.

Authors:  Guadalupe Camarero; Oleg Yu Tyrsin; Chaomei Xiang; Verena Pfeiffer; Sandra Pleiser; Stefan Wiese; Rudolf Götz; Ulf R Rapp
Journal:  Mol Cell Biol       Date:  2006-10       Impact factor: 4.272

Review 3.  Mitogen-activated protein kinases in heart development and diseases.

Authors:  Yibin Wang
Journal:  Circulation       Date:  2007-09-18       Impact factor: 29.690

4.  Identification of novel in vivo phosphorylation sites of the human proapoptotic protein BAD: pore-forming activity of BAD is regulated by phosphorylation.

Authors:  Lisa Polzien; Angela Baljuls; Ulrike E E Rennefahrt; Andreas Fischer; Werner Schmitz; Rene P Zahedi; Albert Sickmann; Renate Metz; Stefan Albert; Roland Benz; Mirko Hekman; Ulf R Rapp
Journal:  J Biol Chem       Date:  2009-08-10       Impact factor: 5.157

5.  CRAF inhibition induces apoptosis in melanoma cells with non-V600E BRAF mutations.

Authors:  K S M Smalley; M Xiao; J Villanueva; T K Nguyen; K T Flaherty; R Letrero; P Van Belle; D E Elder; Y Wang; K L Nathanson; M Herlyn
Journal:  Oncogene       Date:  2008-09-15       Impact factor: 9.867

Review 6.  Signaling to cardiac hypertrophy: insights from human and mouse RASopathies.

Authors:  Valentina Sala; Simona Gallo; Christian Leo; Stefano Gatti; Bruce D Gelb; Tiziana Crepaldi
Journal:  Mol Med       Date:  2012-09-07       Impact factor: 6.354

7.  Effects of HIV-1 protease on cellular functions and their potential applications in antiretroviral therapy.

Authors:  Hailiu Yang; Joseph Nkeze; Richard Y Zhao
Journal:  Cell Biosci       Date:  2012-09-12       Impact factor: 7.133

8.  BAG-1 haplo-insufficiency impairs lung tumorigenesis.

Authors:  Rudolf Götz; Boris W Kramer; Guadalupe Camarero; Ulf R Rapp
Journal:  BMC Cancer       Date:  2004-11-24       Impact factor: 4.430
  8 in total

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