Literature DB >> 14995186

Chemometrical identification of mutations in HIV-1 reverse transcriptase conferring resistance or enhanced sensitivity to arylsulfonylbenzonitriles.

Fátima Rodríguez-Barrios1, Federico Gago.   

Abstract

A comparative binding energy (COMBINE) analysis on a series of nonnucleosidic reverse transcriptase inhibitors yields a QSAR model with high predictive ability and correctly identifies the effect of mutations on relevant protein residues.

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Year:  2004        PMID： 14995186     DOI： 10.1021/ja038893t

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  4 in total

1.  Interaction force diagrams: new insight into ligand-receptor binding.

Authors:  Hooman Shadnia; James S Wright; James M Anderson
Journal:  J Comput Aided Mol Des       Date:  2008-11-07       Impact factor: 3.686

2.  Comprehensive model of wild-type and mutant HIV-1 reverse transciptases.

Authors:  Flavio Ballante; Ira Musmuca; Garland R Marshall; Rino Ragno
Journal:  J Comput Aided Mol Des       Date:  2012-07-26       Impact factor: 3.686

3.  Exploring the binding of BACE-1 inhibitors using comparative binding energy analysis (COMBINE).

Authors:  Shu Liu; Rao Fu; Xiao Cheng; Sheng-Ping Chen; Li-Hua Zhou
Journal:  BMC Struct Biol       Date:  2012-08-27

4.  Structural basis for the development of SARS 3CL protease inhibitors from a peptide mimic to an aza-decaline scaffold.

Authors:  Kenta Teruya; Yasunao Hattori; Yasuhiro Shimamoto; Kazuya Kobayashi; Akira Sanjoh; Atsushi Nakagawa; Eiki Yamashita; Kenichi Akaji
Journal:  Biopolymers       Date:  2016-11-04       Impact factor: 2.505
  4 in total

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