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Literature DB >> 14993447

Cytochromes P450, drugs, and diseases.

F Peter Guengerich¹.

Abstract

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Year: 2003 PMID： 14993447 DOI： 10.1124/mi.3.4.194

Source DB: PubMed Journal: Mol Interv ISSN： 1534-0384

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75 in total

1. Molecular analysis and modeling of inactivation of human CYP2D6 by four mechanism based inactivators.

Authors: Mara Livezey; Leslie D Nagy; Laura E Diffenderfer; Evan J Arthur; David J Hsi; Jeffrey M Holton; Laura Lowe Furge
Journal: Drug Metab Lett Date: 2012-03

2. Metabolization of porphyrinogenic agents in brain: involvement of the phase I drug metabolizing system. A comparative study in liver and kidney.

Authors: Jimena V Lavandera; Alcira Maria Del Carmen Batlle; Ana María Buzaleh
Journal: Cell Mol Neurobiol Date: 2007-08-04 Impact factor: 5.046

3. Preparative synthesis of drug metabolites using human cytochrome P450s 3A4, 2C9 and 1A2 with NADPH-P450 reductase expressed in Escherichia coli.

Authors: Robert B Vail; Michael J Homann; Imad Hanna; Aleksey Zaks
Journal: J Ind Microbiol Biotechnol Date: 2005-03-01 Impact factor: 3.346

4. Population pharmacokinetic analysis of letrozole in Japanese postmenopausal women.

Authors: Hiromi Tanii; Yoshihisa Shitara; Toshiharu Horie
Journal: Eur J Clin Pharmacol Date: 2011-04-15 Impact factor: 2.953

5. Development and evaluation of an in vivo assay in Caenorhabditis elegans for screening of compounds for their effect on cytochrome P450 expression.

Authors: Baby P S Chakrapani; Sandeep Kumar; Jamuna R Subramaniam
Journal: J Biosci Date: 2008-06 Impact factor: 1.826

Cytochromes P450, drugs, and diseases.

1. Molecular analysis and modeling of inactivation of human CYP2D6 by four mechanism based inactivators.

2. Metabolization of porphyrinogenic agents in brain: involvement of the phase I drug metabolizing system. A comparative study in liver and kidney.

3. Preparative synthesis of drug metabolites using human cytochrome P450s 3A4, 2C9 and 1A2 with NADPH-P450 reductase expressed in Escherichia coli.

4. Population pharmacokinetic analysis of letrozole in Japanese postmenopausal women.

5. Development and evaluation of an in vivo assay in Caenorhabditis elegans for screening of compounds for their effect on cytochrome P450 expression.

Review 6. Modeling kinetics of subcellular disposition of chemicals.

Review 7. Biological roles of cytochrome P450 1A1, 1A2, and 1B1 enzymes.

8. The non-coding RNA of the multidrug resistance-linked vault particle encodes multiple regulatory small RNAs.

9. Pharmacokinetic assessment of a five-probe cocktail for CYPs 1A2, 2C9, 2C19, 2D6 and 3A.

10. Variability in drug metabolizing enzyme activity in HIV-infected patients.