Literature DB >> 14993414

Molecular genetics of human cognition.

Edwin J Weeber1, Jonathan M Levenson, J David Sweatt.   

Abstract

Our understanding of the molecular underpinnings of human cognition has been greatly aided by the convergent synergy of clinical, genetic, and signaling research. By identifying the mutated genes that give rise to syndromes of mental retardation or cognitive defects in patients, and by placing the associated gene products within signaling networks, researchers are piecing together how learning occurs and how memories are formed and sustained.

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Mesh:

Year:  2002        PMID: 14993414     DOI: 10.1124/mi.2.6.376

Source DB:  PubMed          Journal:  Mol Interv        ISSN: 1534-0384


  17 in total

1.  Eradicating the mediators of neuronal death with a fine-tooth comb.

Authors:  R Suzanne Zukin
Journal:  Sci Signal       Date:  2010-06-08       Impact factor: 8.192

2.  A mutation in a novel ATP-dependent Lon protease gene in a kindred with mild mental retardation.

Authors:  Joseph J Higgins; Joanna Pucilowska; Roni Q Lombardi; John P Rooney
Journal:  Neurology       Date:  2004-11-23       Impact factor: 9.910

Review 3.  Translational research in central nervous system drug discovery.

Authors:  Orest Hurko; John L Ryan
Journal:  NeuroRx       Date:  2005-10

4.  Gene expression changes in the MAPK pathway in both Fragile X and Down syndrome human neural progenitor cells.

Authors:  Erin L McMillan; Allison L Kamps; Samuel S Lake; Clive N Svendsen; Anita Bhattacharyya
Journal:  Am J Stem Cells       Date:  2012-06-03

Review 5.  Insoluble cellular prion protein and its association with prion and Alzheimer diseases.

Authors:  Wen-Quan Zou; Xiaochen Zhou; Jue Yuan; Xiangzhu Xiao
Journal:  Prion       Date:  2011-07-01       Impact factor: 3.931

Review 6.  Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders.

Authors:  Ted Abel; R Suzanne Zukin
Journal:  Curr Opin Pharmacol       Date:  2008-02       Impact factor: 5.547

7.  Protein profiles associated with context fear conditioning and their modulation by memantine.

Authors:  Md Mahiuddin Ahmed; A Ranjitha Dhanasekaran; Aaron Block; Suhong Tong; Alberto C S Costa; Katheleen J Gardiner
Journal:  Mol Cell Proteomics       Date:  2014-01-27       Impact factor: 5.911

8.  The Ras-GRF1 exchange factor coordinates activation of H-Ras and Rac1 to control neuronal morphology.

Authors:  Huibin Yang; Raymond R Mattingly
Journal:  Mol Biol Cell       Date:  2006-02-15       Impact factor: 4.138

9.  The cAMP responsive element-binding (CREB)-1 gene increases risk of major psychiatric disorders.

Authors:  X Xiao; C Zhang; M Grigoroiu-Serbanescu; L Wang; L Li; D Zhou; T-F Yuan; C Wang; H Chang; Y Wu; Y Li; D-D Wu; Y-G Yao; M Li
Journal:  Mol Psychiatry       Date:  2017-11-21       Impact factor: 15.992

10.  Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility.

Authors:  M Li; X-J Luo; M Rietschel; C M Lewis; M Mattheisen; B Müller-Myhsok; S Jamain; M Leboyer; M Landén; P M Thompson; S Cichon; M M Nöthen; T G Schulze; P F Sullivan; S E Bergen; G Donohoe; D W Morris; A Hargreaves; M Gill; A Corvin; C Hultman; A W Toga; L Shi; Q Lin; H Shi; L Gan; A Meyer-Lindenberg; D Czamara; C Henry; B Etain; J C Bis; M A Ikram; M Fornage; S Debette; L J Launer; S Seshadri; S Erk; H Walter; A Heinz; F Bellivier; J L Stein; S E Medland; A Arias Vasquez; D P Hibar; B Franke; N G Martin; M J Wright; B Su
Journal:  Mol Psychiatry       Date:  2013-04-09       Impact factor: 15.992

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