Literature DB >> 14991428

Foster placed children prenatally exposed to poly-substances--attention-related problems at ages 2 and 4 1/2.

K Slinning1.   

Abstract

This paper reports on a prospective, longitudinal study of children prenatally exposed to poly-substances, who were reared under minimal postnatal risk conditions. The aim of the study was to examine whether the substance-exposed group exhibited a higher level of attention-related problems than a group of age-matched, nonexposed children. The substance-exposed children (n = 42) evinced significant elevated levels of impulsivity and attention problems on the CBCL and on the ADHD rating scale at ages 2 and 4 1/2 as compared to the non-exposed peers (n = 50). The severity of the attention problems in the substance-exposed group was related to dysfunction in the area of perceptual performance and motor abilities assessed on the McCarthy scales. This finding lends support to the hypothesis of a neurological basis of the behavioral problems. The combination of attention problems and specific cognitive deficits indicates that the children exposed to poly-substances in utero had symptoms associated with ADHD/DAMP. The study suggests that even if children experience adequate care after birth, the accumulation of risk factors associated with prenatal substance exposure is still a potential contributor to impulsivity and attention-related problems in preschool children.

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Year:  2004        PMID: 14991428     DOI: 10.1007/s00787-004-0350-x

Source DB:  PubMed          Journal:  Eur Child Adolesc Psychiatry        ISSN: 1018-8827            Impact factor:   4.785


  16 in total

Review 1.  Areas for future investment in the field of ADHD: preschoolers and clinical networks.

Authors:  Manfred Döpfner; Aribert Rothenberger; Edmund Sonuga-Barke
Journal:  Eur Child Adolesc Psychiatry       Date:  2004       Impact factor: 4.785

Review 2.  Consequences of prenatal toxin exposure for mental health in children and adolescents: a systematic review.

Authors:  Justin H G Williams; Louise Ross
Journal:  Eur Child Adolesc Psychiatry       Date:  2007-01-02       Impact factor: 4.785

3.  Effects of opioid use in pregnancy on pediatric development and behaviour in children older than age 2: Systematic review.

Authors:  Stephanie Welton; Brittany Blakelock; Sharen Madden; Len Kelly
Journal:  Can Fam Physician       Date:  2019-12       Impact factor: 3.275

4.  Risk factors for the development of emotional and behavioural problems in children born to drug-dependent mothers.

Authors:  Hans-Christoph Steinhausen; Serena Dal Mas; Christoph Ledermann; Christa Winkler Metzke
Journal:  Eur Child Adolesc Psychiatry       Date:  2006-09-08       Impact factor: 4.785

5.  White matter characteristics and cognition in prenatally opiate- and polysubstance-exposed children: a diffusion tensor imaging study.

Authors:  K B Walhovd; L T Westlye; V Moe; K Slinning; P Due-Tønnessen; A Bjørnerud; A van der Kouwe; A M Dale; A M Fjell
Journal:  AJNR Am J Neuroradiol       Date:  2010-03-04       Impact factor: 3.825

6.  Perinatal Morphine Exposure Leads to Sex-Dependent Executive Function Deficits and Microglial Changes in Mice.

Authors:  Brittany L Smith; Tess A Guzman; Alexander H Brendle; Collin J Laaker; Alexis Ford; Adam R Hiltz; Junfang Zhao; Kenneth D R Setchell; Teresa M Reyes
Journal:  eNeuro       Date:  2022-10-17

7.  Volumetric cerebral characteristics of children exposed to opiates and other substances in utero.

Authors:  K B Walhovd; V Moe; K Slinning; P Due-Tønnessen; A Bjørnerud; A M Dale; A van der Kouwe; B T Quinn; B Kosofsky; D Greve; B Fischl
Journal:  Neuroimage       Date:  2007-04-25       Impact factor: 6.556

8.  Mother-Child Interaction and Early Language Skills in Children Born to Mothers with Substance Abuse and Psychiatric Problems.

Authors:  Kristin J Haabrekke; Torill Siqveland; Lars Smith; Tore Wentzel-Larsen; Kristine B Walhovd; Vibeke Moe
Journal:  Child Psychiatry Hum Dev       Date:  2015-10

Review 9.  Prenatal opioid exposure and vulnerability to future substance use disorders in offspring.

Authors:  Yaa Abu; Sabita Roy
Journal:  Exp Neurol       Date:  2021-01-29       Impact factor: 5.330

Review 10.  Prenatal Opioid Exposure and ADHD Childhood Symptoms: A Meta-Analysis.

Authors:  Ashlyn N Schwartz; Lucia M Reyes; Laurie L Meschke; Kristina W Kintziger
Journal:  Children (Basel)       Date:  2021-02-04
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