Literature DB >> 14991420

[Fasciitis nodularis pseudosarcomatosa. A difficult differential diagnosis in the head-neck area].

K A Grötz1, B Al-Nawas, U Bettendorf.   

Abstract

INTRODUCTION: Nodular fasciitis (nF) was first described in 1955 by Konwaler et al. as a benign fibroblastic proliferation. The onset of the disease occurs suddenly as a solitary tumor reaching a size of 10 to 50 mm in a few weeks. Relapse is rare and spontaneous remission frequent. The literature points out histologic similarities to a sarcoma. CASE: The 57 year old female patient presented a spheroid, coarse, nonadherent, slightly painful tumor of the left paramandibular region. The history was inconspicuous. The B-scan sonography revealed a spheroid, anechoic, defined mass of 10-11 mm. The palpatory dimension increased noticeably during the following 2 weeks. Under local anesthesia the suspected lymph node was exposed via intraoral approach. Intraoperatively a non-capsulated, coarse, adherent, spheroid node of 25 mm was resected subtotally to preserve the marginal branch of the facial nerve. Histologically a fibroblastic cell-rich proliferation with mucoid milieu and few mitosis was found. No atypical cells or nuclei were observed and the proliferation reached fascial parts. DISCUSSION: Based on clinical findings the diagnosis nF cannot be proven. Ultrasound and clinical findings suppose a lymphadenopathia, whereas the dynamics points out a malignant tumor. Therefore, histologic assurance after diagnosis is mandatory. In case of vulnerable anatomic structures in vicinity, the absence of a capsule should lead to partial resection despite of a total excision. The histology plays a primary role to avoid surgical overtherapy.

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Year:  2003        PMID: 14991420     DOI: 10.1007/s10006-003-0513-9

Source DB:  PubMed          Journal:  Mund Kiefer Gesichtschir        ISSN: 1432-9417


  18 in total

1.  Subcutaneous pseudosarcomatous fibromatosis (fasciitis).

Authors:  B E KONWALER; L KEASBEY; L KAPLAN
Journal:  Am J Clin Pathol       Date:  1955-03       Impact factor: 2.493

2.  Intradermal variant of nodular 'fasciitis'.

Authors:  J R Goodlad; C D Fletcher
Journal:  Histopathology       Date:  1990-12       Impact factor: 5.087

Review 3.  Nodular fasciitis of the vulva: a study of six cases and literature review.

Authors:  J X O'Connell; R H Young; G P Nielsen; A E Rosenberg; T C Bainbridge; P B Clement
Journal:  Int J Gynecol Pathol       Date:  1997-04       Impact factor: 2.762

4.  Cranial fasciitis simulating histiocytosis.

Authors:  R Adler; C A Wong
Journal:  J Pediatr       Date:  1986-07       Impact factor: 4.406

5.  Nodular fasciitis.

Authors:  P W Allen
Journal:  Pathology       Date:  1972-01       Impact factor: 5.306

6.  Nodular fasciitis: a case with unusual clinical presentation initially diagnosed by aspiration cytology.

Authors:  S S Fernando; S Gune; S George; P Van Gelderen
Journal:  Cytopathology       Date:  1993       Impact factor: 2.073

7.  [Nodular fascitis].

Authors:  R Flesch; P Hermanek
Journal:  Fortschr Med       Date:  1976-04-15

8.  Nodular fasciitis. Its morphologic spectrum and immunohistochemical profile.

Authors:  E A Montgomery; J M Meis
Journal:  Am J Surg Pathol       Date:  1991-10       Impact factor: 6.394

Review 9.  Connective tissue tumors.

Authors:  Bernhard Zelger
Journal:  Recent Results Cancer Res       Date:  2002

10.  A case of nodular fasciitis of the bladder.

Authors:  H Senoh; N Nonomura; H Akai; M Takemoto
Journal:  Hinyokika Kiyo       Date:  1994-05
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