Literature DB >> 14990761

Neurometabolic functioning and neuropsychological correlates in children with ADHD-H: preliminary findings.

Helen Courvoisie1, Stephen R Hooper, Camille Fine, Lester Kwock, Mauricio Castillo.   

Abstract

Proton magnetic resonance spectroscopy (MRS) and neuropsychological testing were conducted on 8 children with attention-deficit/hyperactivity disorder (ADHD-H), with no learning disabilities or comorbidities and 8 controls. Magnetic resonance spectroscopy revealed increased Glutamate/Glutamine in both frontal areas, and increased N-acetyl aspartate and Choline in the right frontal area of the ADHD-H subjects. Neuropsychological testing revealed few within- and between-group differences. Findings related to frontal lobe dysfunction in ADHD-H subjects were noted. N-acetylasparte/creatine (NAA/Creatine) in the right frontal region, and myoinositol/creatine (Myo inositol/Creatine) in the right and left frontal regions appear to be highly associated with the regulation of sensorimotor, language, and memory and learning functioning in children with ADHD-H.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 14990761     DOI： 10.1176/jnp.16.1.63

Source DB:  PubMed          Journal:  J Neuropsychiatry Clin Neurosci        ISSN： 0895-0172            Impact factor:   2.198


  37 in total

1.  Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder.

Authors:  Josephine Elia; Joseph T Glessner; Kai Wang; Nagahide Takahashi; Corina J Shtir; Dexter Hadley; Patrick M A Sleiman; Haitao Zhang; Cecilia E Kim; Reid Robison; Gholson J Lyon; James H Flory; Jonathan P Bradfield; Marcin Imielinski; Cuiping Hou; Edward C Frackelton; Rosetta M Chiavacci; Takeshi Sakurai; Cara Rabin; Frank A Middleton; Kelly A Thomas; Maria Garris; Frank Mentch; Christine M Freitag; Hans-Christoph Steinhausen; Alexandre A Todorov; Andreas Reif; Aribert Rothenberger; Barbara Franke; Eric O Mick; Herbert Roeyers; Jan Buitelaar; Klaus-Peter Lesch; Tobias Banaschewski; Richard P Ebstein; Fernando Mulas; Robert D Oades; Joseph Sergeant; Edmund Sonuga-Barke; Tobias J Renner; Marcel Romanos; Jasmin Romanos; Andreas Warnke; Susanne Walitza; Jobst Meyer; Haukur Pálmason; Christiane Seitz; Sandra K Loo; Susan L Smalley; Joseph Biederman; Lindsey Kent; Philip Asherson; Richard J L Anney; J William Gaynor; Philip Shaw; Marcella Devoto; Peter S White; Struan F A Grant; Joseph D Buxbaum; Judith L Rapoport; Nigel M Williams; Stanley F Nelson; Stephen V Faraone; Hakon Hakonarson
Journal:  Nat Genet       Date:  2011-12-04       Impact factor: 38.330

2.  EEG power spectral slope differs by ADHD status and stimulant medication exposure in early childhood.

Authors:  Madeline M Robertson; Sarah Furlong; Bradley Voytek; Thomas Donoghue; Charlotte A Boettiger; Margaret A Sheridan
Journal:  J Neurophysiol       Date:  2019-10-16       Impact factor: 2.714

3.  Effect of diet on brain metabolites and behavior in spontaneously hypertensive rats.

Authors:  Ana A Liso Navarro; Elif M Sikoglu; Cailin R Heinze; Ryan C Rogan; Vivienne A Russell; Jean A King; Constance M Moore
Journal:  Behav Brain Res       Date:  2014-05-19       Impact factor: 3.332

Review 4.  Neuroimaging of children following prenatal drug exposure.

Authors:  Chris Derauf; Minal Kekatpure; Nurunisa Neyzi; Barry Lester; Barry Kosofsky
Journal:  Semin Cell Dev Biol       Date:  2009-03-13       Impact factor: 7.727

5.  Differential neuroimaging indices in prefrontal white matter in prenatal alcohol-associated ADHD versus idiopathic ADHD.

Authors:  Joseph O'Neill; Mary J O'Connor; Victor Yee; Ronald Ly; Katherine Narr; Jeffrey R Alger; Jennifer G Levitt
Journal:  Birth Defects Res       Date:  2019-01-29       Impact factor: 2.344

6.  Genetic predisposition and early life experience interact to determine glutamate transporter (GLT1) and solute carrier family 12 member 5 (KCC2) levels in rat hippocampus.

Authors:  Toni-Lee Sterley; Fleur M Howells; Jacqueline J Dimatelis; Vivienne A Russell
Journal:  Metab Brain Dis       Date:  2016-02       Impact factor: 3.584

7.  Adolescent D-amphetamine treatment in a rodent model of ADHD: Pro-cognitive effects in adolescence without an impact on cocaine cue reactivity in adulthood.

Authors:  Chloe J Jordan; Danielle M Taylor; Linda P Dwoskin; Kathleen M Kantak
Journal:  Behav Brain Res       Date:  2015-10-20       Impact factor: 3.332

8.  Randomized double-blind placebo-controlled trial of lithium in youths with severe mood dysregulation.

Authors:  Daniel P Dickstein; Kenneth E Towbin; Jan Willem Van Der Veen; Brendan A Rich; Melissa A Brotman; Lisa Knopf; Laura Onelio; Daniel S Pine; Ellen Leibenluft
Journal:  J Child Adolesc Psychopharmacol       Date:  2009-02       Impact factor: 2.576

9.  Attention-deficit hyperactivity disorder (ADHD) and glial integrity: S100B, cytokines and kynurenine metabolism--effects of medication.

Authors:  Robert D Oades; Maria R Dauvermann; Benno G Schimmelmann; Markus J Schwarz; Aye-Mu Myint
Journal:  Behav Brain Funct       Date:  2010-05-28       Impact factor: 3.759

10.  Differentiating attention-deficit/hyperactivity disorder inattentive and combined types: a (1)H-magnetic resonance spectroscopy study of fronto-striato-thalamic regions.

Authors:  Pedro E M S Ferreira; André Palmini; Claiton H D Bau; Eugenio Horacio Grevet; João Rubião Hoefel; Luis Augusto Rohde; Maurício Anés; Eloisa Elena Ferreira; Paulo Belmonte-de-Abreu
Journal:  J Neural Transm (Vienna)       Date:  2009-04-28       Impact factor: 3.575
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.