Literature DB >> 14990296

[Psoriasis and osteomalacia. Report of a new case].

N Raissouni1, E Benyahya, S Janani, R Bennis, O Mkinsi.   

Abstract

INTRODUCTION: The association psoriasis and osteomalacia is very rare. EXEGESIS: We report the case of a young girl, aged 17, who was consulting for ostealgia and erythematic and squamous cutaneous lesions. She had a staturo-ponderal delay, ostealgia and a bending of the general state. The osteo-articular examination showed a sternal protrusion with painful limitation of the movements of all joints. The dermatologic examination noted a dry erythrodermis to hick squamous with scalp's crush. The biological (hypocalcaemia, diminished urinary calcium) and radiological (demineralized bone with Looser-Milkmann fractures) results suggest an osteomalacia, diagnostic confirmed by the bone histological study that found out osteoid lines. The cutaneous biopsy was compatible with psoriasis diagnosis. A vitamino-calcic treatment associated to local nursing was undertaken. The evolution was favorable, noted by a cutaneous bleaching with a return back of the articular function. The present receding is of nine years.
CONCLUSION: Different studies underlined that outside of its action on the phosphocalcic metabolism, the vitamin D acts on the skin, especially on the proliferation of the keratinocytes that allowed its indication in the treatment of the psoriasis.

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Year:  2004        PMID: 14990296     DOI: 10.1016/j.revmed.2003.11.013

Source DB:  PubMed          Journal:  Rev Med Interne        ISSN: 0248-8663            Impact factor:   0.728


  1 in total

1.  Osteomalacia associated with cutaneous psoriasis as the presenting feature of coeliac disease: a case report.

Authors:  Faten Frikha; Mouna Snoussi; Zouhir Bahloul
Journal:  Pan Afr Med J       Date:  2012-03-27
  1 in total

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