Literature DB >> 14987959

Alterations in morning cortisol associated with PTSD in women with breast cancer.

Linda J Luecken1, Barbara Dausch, Vanessa Gulla, Richard Hong, Bruce E Compas.   

Abstract

OBJECTIVE: Diagnosis and treatment of breast cancer can be a stressful experience, putting women at risk of posttraumatic stress disorder (PTSD). The current study investigated morning cortisol levels in newly diagnosed (i.e., within 6 months) breast cancer patients.
METHODS: Structured DSM-IV interviews determined current and past incidence of PTSD and major depressive disorder (MDD) in 71 women with Stage 0-3 breast cancer.
RESULTS: Significantly decreased plasma cortisol was found in women meeting current or lifetime criteria for PTSD or past diagnosis of MDD.
CONCLUSIONS: These results reinforce the importance for both psychological and physiological outcomes of a clinical evaluation of both current and past psychiatric status in newly diagnosed cancer patients.

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Year:  2004        PMID: 14987959     DOI: 10.1016/S0022-3999(03)00561-0

Source DB:  PubMed          Journal:  J Psychosom Res        ISSN: 0022-3999            Impact factor:   3.006


  11 in total

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