| Literature DB >> 14987890 |
Neil Stollman1, Jeffrey B Raskin.
Abstract
Colonic diverticulosis refers to small outpouchings from the colonic lumen due to mucosal herniation through the colonic wall at sites of vascular perforation. Abnormal colonic motility and inadequate intake of dietary fibre have been implicated in its pathogenesis. This acquired abnormality is typically found in developed countries, and its prevalence rises with age. Most patients affected will remain entirely asymptomatic; however, 10-20% of those affected can manifest clinical syndromes, mainly diverticulitis and diverticular haemorrhage. As our elderly population grows, we can anticipate a concomitant rise in the number of patients with diverticular disease. Here, we review the incidence, pathophysiology, clinical presentation, and management of diverticular disease of the colon and its complications.Entities:
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Year: 2004 PMID: 14987890 DOI: 10.1016/S0140-6736(04)15597-9
Source DB: PubMed Journal: Lancet ISSN: 0140-6736 Impact factor: 79.321