Literature DB >> 14986772

The concept of placebo.

Zbigniew Szawarski1.   

Abstract

This paper attempts to define the concept of placebo as it is used in the clinical context The author claims that X is a placebo if and only if X has such a property dp, that whenever in a therapeutic situation T a stimulus S appears, then in attending conditions A, it will cause a beneficial reaction R in the patient. Formally, the same structure may be used to define any pharmacologically active drug. The main difference between the drug and a placebo is in the range of possible substitutions for X and the property d. For the active drug there is only one possible substitution for X and property d and it can be scientifically explained why, and how the drug works. In the case of a placebo a set of possible substitutions for X and d is open, and so far it is impossible to offer any scientifically valid explanation of the action mechanism of placebo.

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Year:  2004        PMID: 14986772     DOI: 10.1007/s11948-004-0063-z

Source DB:  PubMed          Journal:  Sci Eng Ethics        ISSN: 1353-3452            Impact factor:   3.525


  4 in total

1.  The powerful placebo.

Authors:  H K BEECHER
Journal:  J Am Med Assoc       Date:  1955-12-24

2.  The placebo concept in medicine and psychiatry.

Authors:  A Grünbaum
Journal:  Psychol Med       Date:  1986-02       Impact factor: 7.723

3.  'Tonic', 'fuel' and 'food': social and symbolic aspects of the long-term use of psychotropic drugs.

Authors:  C G Helman
Journal:  Soc Sci Med B       Date:  1981-10

4.  Neuropharmacological dissection of placebo analgesia: expectation-activated opioid systems versus conditioning-activated specific subsystems.

Authors:  M Amanzio; F Benedetti
Journal:  J Neurosci       Date:  1999-01-01       Impact factor: 6.167

  4 in total
  1 in total

Review 1.  Placebo: its action and place in health research today--summary and conclusions.

Authors:  Raymond E Spier
Journal:  Sci Eng Ethics       Date:  2004-01       Impact factor: 3.525

  1 in total

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