Panagiotis Karadimas1, Evrydiki A Bouzas. 1. Medical Retina Unit, 1st Department of Ophthalmology, Henry Dunant Hospital, 107 Mesogion Avenue, 11526 Athens, Greece. t_karadimas@yahoo.com
Abstract
PURPOSE: To evaluate whether exposure to glucocorticoids represents a risk factor for the development of central serous chorioretinopathy (CSCR). METHODS: Prospective, case-control study. Thirty-eight consecutive patients with acute CSCR were asked to answer a specific questionnaire regarding the use of glucocorticoids, in any form, during the last month before the onset of the symptoms. An age- and sex-matched control group was also recruited. It consisted of patients attending the outpatient department for a condition other than CSCR, who were asked to answer the same questionnaire. RESULTS: Use of glucocorticoids was recorded in 11 of 38 patients (28.9%) with CSCR; 8 of them were men and 3 women. In the control group, use of glucocorticoids was recorded in 2 of 38 patients (5.2%), 1 man and 1 woman. The difference between the two groups is statistically significant (odds ratio=7.33, 95% CI=1.49-35.85, P=0.006). CONCLUSION: In this prospective, case-control study, we found that glucocorticoid use represents a risk factor for the development of CSCR.
PURPOSE: To evaluate whether exposure to glucocorticoids represents a risk factor for the development of central serous chorioretinopathy (CSCR). METHODS: Prospective, case-control study. Thirty-eight consecutive patients with acute CSCR were asked to answer a specific questionnaire regarding the use of glucocorticoids, in any form, during the last month before the onset of the symptoms. An age- and sex-matched control group was also recruited. It consisted of patients attending the outpatient department for a condition other than CSCR, who were asked to answer the same questionnaire. RESULTS: Use of glucocorticoids was recorded in 11 of 38 patients (28.9%) with CSCR; 8 of them were men and 3 women. In the control group, use of glucocorticoids was recorded in 2 of 38 patients (5.2%), 1 man and 1 woman. The difference between the two groups is statistically significant (odds ratio=7.33, 95% CI=1.49-35.85, P=0.006). CONCLUSION: In this prospective, case-control study, we found that glucocorticoid use represents a risk factor for the development of CSCR.
Authors: M K Tittl; R F Spaide; D Wong; E Pilotto; L A Yannuzzi; Y L Fisher; B Freund; D R Guyer; J S Slakter; J A Sorenson Journal: Am J Ophthalmol Date: 1999-07 Impact factor: 5.258
Authors: Cynthia A Carvalho-Recchia; Lawrence A Yannuzzi; Silvana Negrão; Richard F Spaide; K Bailey Freund; Hanna Rodriguez-Coleman; Marcio Lenharo; Tomohiro Iida Journal: Ophthalmology Date: 2002-10 Impact factor: 12.079