Literature DB >> 14984888

Abnormalities in MRI-measured signal intensity in the corpus callosum in schizophrenia.

Vaibhav A Diwadkar1, Michael D DeBellis, John A Sweeney, Jay W Pettegrew, Matcheri S Keshavan.   

Abstract

The microstructural integrity of the corpus callosum (CC) in first-episode schizophrenia patients was assessed by measuring the signal intensity (SI) in T1-weighted MRI images. Analyses revealed that compared to both healthy controls and non-schizophrenic patients, schizophrenia patients showed reductions in SI in all the callosal subregions, the genu, body, isthmus and splenium in first-episode schizophrenia. These results indicate that schizophrenia is characterized by pathology of this principal interhemispheric commissure; the abnormalities may reflect distributed (rather than localized) interhemispheric disconnectivity that extends beyond the heteromodal association cortices.

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Year:  2004        PMID： 14984888     DOI： 10.1016/S0920-9964(03)00098-7

Source DB:  PubMed          Journal:  Schizophr Res        ISSN： 0920-9964            Impact factor:   4.939


  14 in total

1.  Probabilistic topography of human corpus callosum using cytoarchitectural parcellation and high angular resolution diffusion imaging tractography.

Authors:  Yi-Ping Chao; Kuan-Hung Cho; Chun-Hung Yeh; Kun-Hsien Chou; Jyh-Horng Chen; Ching-Po Lin
Journal:  Hum Brain Mapp       Date:  2009-10       Impact factor: 5.038

2.  White matter microstructure in untreated first episode bipolar disorder with psychosis: comparison with schizophrenia.

Authors:  Lisa H Lu; Xiaohong Joe Zhou; Sarah K Keedy; James L Reilly; John A Sweeney
Journal:  Bipolar Disord       Date:  2011 Nov-Dec       Impact factor: 6.744

3.  Cerebral connectivity and psychotic personality traits. A diffusion tensor imaging study.

Authors:  Umberto Volpe; Andrea Federspiel; Armida Mucci; Thomas Dierks; Anders Frank; Lars-Olof Wahlund; Silvana Galderisi; Mario Maj
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2008-02-23       Impact factor: 5.270

4.  A comparative study of corpus callosum size and signal intensity in capuchin monkeys (Cebus apella) and chimpanzees (Pan troglodytes).

Authors:  K A Phillips; N Kapfenberger; W D Hopkins
Journal:  Neuroscience       Date:  2009-02-03       Impact factor: 3.590

5.  A longitudinal study of the corpus callosum in chronic schizophrenia.

Authors:  Serge A Mitelman; Yekaterina K Nikiforova; Emily L Canfield; Erin A Hazlett; Adam M Brickman; Lina Shihabuddin; Monte S Buchsbaum
Journal:  Schizophr Res       Date:  2009-08-26       Impact factor: 4.939

6.  Quantitative proton MR spectroscopy findings in the corpus callosum of patients with schizophrenia suggest callosal disconnection.

Authors:  K Aydin; A Ucok; S Cakir
Journal:  AJNR Am J Neuroradiol       Date:  2007-09-26       Impact factor: 3.825

7.  Targeting of neurotrophic factors, their receptors, and signaling pathways in the developmental neurotoxicity of organophosphates in vivo and in vitro.

Authors:  Theodore A Slotkin; Frederic J Seidler; Fabio Fumagalli
Journal:  Brain Res Bull       Date:  2008-02-01       Impact factor: 4.077

8.  Reduced gray to white matter tissue intensity contrast in schizophrenia.

Authors:  Li Kong; Christina Herold; Bram Stieltjes; Marco Essig; Ulrich Seidl; Robert Christian Wolf; Torsten Wüstenberg; Marc Montgomery Lässer; Lena Anna Schmid; Knut Schnell; Dusan Hirjak; Philipp Arthur Thomann
Journal:  PLoS One       Date:  2012-05-15       Impact factor: 3.240

9.  Joint source based morphometry identifies linked gray and white matter group differences.

Authors:  Lai Xu; Godfrey Pearlson; Vince D Calhoun
Journal:  Neuroimage       Date:  2008-10-18       Impact factor: 6.556

10.  The Frizzled 3 gene is associated with methamphetamine psychosis in the Japanese population.

Authors:  Makiko Kishimoto; Hiroshi Ujike; Yuko Okahisa; Tatsuya Kotaka; Manabu Takaki; Masafumi Kodama; Toshiya Inada; Mitsuhiko Yamada; Naohisa Uchimura; Nakao Iwata; Ichiro Sora; Masaomi Iyo; Norio Ozaki; Shigetoshi Kuroda
Journal:  Behav Brain Funct       Date:  2008-08-15       Impact factor: 3.759
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