| Literature DB >> 14982798 |
Abstract
We extended a computer simulation of viral intracellular growth to study a parasitic antiviral strategy that diverts the viral replicase toward parasite growth. This strategy inhibited virus growth over a wide range of conditions, while minimizing host cell perturbations. Such parasitic strategies may inhibit the development of drug-resistant virus strains.Mesh:
Substances:
Year: 2004 PMID: 14982798 PMCID: PMC353149 DOI: 10.1128/AAC.48.3.1017-1020.2004
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191