| Literature DB >> 14980673 |
Jill A Jablonowski1, Wenying Chai, Xiaobing Li, Dale A Rudolph, William V Murray, Mark A Youngman, Scott L Dax, Diane Nepomuceno, Pascal Bonaventure, Timothy W Lovenberg, Nicholas I Carruthers.
Abstract
Through SAR studies of a piperidinylindoline cinnamide HTS lead, the first potent, non-peptide, low molecular weight selective Neuropeptide Y Y2 (NPY Y2) antagonists have been synthesized. The SAR studies around the piperidinyl, the indolinyl, and the cinnamyl moieties are discussed.Entities:
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Year: 2004 PMID： 14980673 DOI： 10.1016/j.bmcl.2003.12.057
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823