| Literature DB >> 14980669 |
Yun He1, Jun Yang, Baogen Wu, Lisa Risen, Eric E Swayze.
Abstract
A series of novel benzimidazole derivatives were synthesized via parallel solution-phase chemistry. Many of these compounds were found to inhibit the growth of Staphylococcus aureus and Escherichia coli. Several analogues exhibited low micromolar minimal inhibitory concentrations (MIC) against both Gram-positive and Gram-negative bacteria of clinical relevance and could serve as leads for further optimizations for antibacterial research.Entities:
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Year: 2004 PMID： 14980669 DOI： 10.1016/j.bmcl.2003.12.051
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823