Literature DB >> 14980648

New heteroarylbenzenesulphonamides as matrix metalloproteinase inhibitors.

Frédéric Delbecq1, Guy Cordonnier, Nicole Pommery, Didier Barbry, Jean-Pierre Hénichart.   

Abstract

A series of derivatives of 2,4- and 2,5-thiazolyl- or oxazolylbenzenesulphonamides has been prepared and evaluated as potential MMP inhibitors. The thiazole 15b have been found to exhibit MMP-2 and MMP-9 inhibitions higher than reference compounds GI 129471 and CGS 27023A.

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Year:  2004        PMID： 14980648     DOI： 10.1016/j.bmcl.2003.12.076

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  3 in total

1.  Thiazole, oxadiazole, and carboxamide derivatives of artemisinin are highly selective and potent inhibitors of Toxoplasma gondii.

Authors:  Christopher P Hencken; Lorraine Jones-Brando; Claudia Bordón; Remo Stohler; Bryan T Mott; Robert Yolken; Gary H Posner; Lauren E Woodard
Journal:  J Med Chem       Date:  2010-05-13       Impact factor: 7.446

2.  3-substituted indazoles as configurationally locked 4EGI-1 mimetics and inhibitors of the eIF4E/eIF4G interaction.

Authors:  Revital Yefidoff-Freedman; Ting Chen; Rupam Sahoo; Limo Chen; Gerhard Wagner; Jose A Halperin; Bertal H Aktas; Michael Chorev
Journal:  Chembiochem       Date:  2014-01-23       Impact factor: 3.164

3.  Switching the site-selectivity of C-H activation in aryl sulfonamides containing strongly coordinating N-heterocycles.

Authors:  Yi Dong; XuePeng Zhang; Jiajing Chen; Wenxing Zou; Songwen Lin; Heng Xu
Journal:  Chem Sci       Date:  2019-08-12       Impact factor: 9.825
  3 in total

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