| Literature DB >> 14980639 |
Vishnu K Tandon1, Rakeshwar B Chhor, Ravindra V Singh, Sanjay Rai, Dharmendra B Yadav.
Abstract
A series of 1,4-naphthoquinone derivatives were synthesized and tested for antifungal and antitumor activity against a number of fungal disease causative species and Walker 256 carcinoma cell lines. The results show that the compounds 8a,e and 11b possess pronounced antifungal profile where as 7b and f were found to be active against Walker 256 carcinoma cell lines. Moreover 7c and 11a showed inhibitory effect against reverse transcriptase enzyme from Rauscher Murine Leukemia Virus.Entities:
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Year: 2004 PMID： 14980639 DOI： 10.1016/j.bmcl.2004.01.002
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823