Literature DB >> 14980600

Synthesis and antihyperglycemic activity of chalcone based aryloxypropanolamines.

M Satyanarayana1, Priti Tiwari, Brajendra K Tripathi, A K Srivastava, Ram Pratap.   

Abstract

A series of aryloxypropanolamines (5a-r) of different chalcones (3a-e) were synthesized and evaluated for antihyperglycemic activity in sucrose loaded (SLM) and streptozotocin (STZ) induced diabetic animal models. Among them compounds 5a, g, m, o, p and r showed significant reduction in blood glucose levels in both SLM and STZ animal models.

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Year:  2004        PMID： 14980600     DOI： 10.1016/j.bmc.2003.12.026

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN： 0968-0896            Impact factor:   3.641


  31 in total

1.  4'-Acetamidochalcone derivatives as potential antinociceptive agents.

Authors:  Fátima de Campos-Buzzi; Pâmela Padaratz; Aleandra Vergilina Meira; Rogério Corrêa; Ricardo José Nunes; Valdir Cechinel-Filho
Journal:  Molecules       Date:  2007-04-30       Impact factor: 4.411

2.  (E)-3-(4-Chloro-phen-yl)-1-(1-naphth-yl)prop-2-en-1-one.

Authors:  Grzegorz Dutkiewicz; S Samshuddin; B Narayana; H S Yathirajan; Maciej Kubicki
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-11-28

3.  (E)-3-[4-(Dodec-yloxy)phen-yl]-1-(2-hydroxy-phen-yl)prop-2-en-1-one.

Authors:  Ibrahim Abdul Razak; Hoong-Kun Fun; Zainab Ngaini; Siti Muhaini Haris Fadzillah; Hasnain Hussain
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-04-25

4.  (E)-3-[4-(Dec-yloxy)phen-yl]-1-(4-hydroxy-phen-yl)prop-2-en-1-one.

Authors:  Ibrahim Abdul Razak; Hoong-Kun Fun; Zainab Ngaini; Norashikin Irdawaty Abd Rahman; Hasnain Hussain
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-04-22

5.  (E)-3-[4-(Hex-yloxy)phen-yl]-1-(4-hydroxy-phen-yl)prop-2-en-1-one.

Authors:  Ibrahim Abdul Razak; Hoong-Kun Fun; Zainab Ngaini; Norashikin Irdawaty Abd Rahman; Hasnain Hussain
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-05-29

6.  (E)-3-(4-Decyl-oxyphen-yl)-1-(2-hydroxy-phen-yl)prop-2-en-1-one.

Authors:  Zainab Ngaini; Norashikin Irdawaty Abd Rahman; Hasnain Hussain; Ibrahim Abdul Razak; Hoong-Kun Fun
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-03-28

7.  Synthesis and activity of a new series of (Z)-3-phenyl-2-benzoylpropenoic acid derivatives as aldose reductase inhibitors.

Authors:  Shao-Jie Wang; Ju-Fang Yan; Dong Hao; Xin-Wen Niu; Mao-Sheng Cheng
Journal:  Molecules       Date:  2007-04-30       Impact factor: 4.411

8.  Design, Synthesis, Characterization and in vivo Antidiabetic Activity Evaluation of Some Chalcone Derivatives.

Authors:  Semere Welday Kahssay; Gebremedhin Solomon Hailu; Kebede Taye Desta
Journal:  Drug Des Devel Ther       Date:  2021-07-17       Impact factor: 4.162

9.  (E)-1-(4-Decyl-oxyphen-yl)-3-(2-hy-droxy-phen-yl)prop-2-en-1-one.

Authors:  Zainab Ngaini; Siti Muhaini Haris Fadzillah; Hasnain Hussain; Ibrahim Abdul Razak; Safra Izuani Jama Asik
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-09-15

10.  (3E)-11,16-Dioxatricyclo-[15.4.0.0(5,10)]henicosa-1(21),3,5,7,9,17,19-heptaen-2-one.

Authors:  Gnanavelu Ganesh; Santhanagopalan Purushothaman; Piskala Subburaman Kannan; Raghavachary Raghunathan; Arunachalathevar Subbiahpandi
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-02-23
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