| Literature DB >> 14977861 |
Peter G Wells1, Peter I Mackenzie, Jayanta Roy Chowdhury, Chantal Guillemette, Philip A Gregory, Yuji Ishii, Antony J Hansen, Fay K Kessler, Perry M Kim, Namita Roy Chowdhury, Joseph K Ritter.
Abstract
This article is an updated report of a symposium held at the June 2000 annual meeting of the American Society for Pharmacology and Experimental Therapeutics in Boston. The symposium was sponsored by the ASPET Divisions for Drug Metabolism and Molecular Pharmacology. The report covers research from the authors' laboratories on the structure and regulation of UDP-glucuronosyltransferase (UGT) genes, glucuronidation of xenobiotics and endobiotics, the toxicological relevance of UGTs, the role of UGT polymorphisms in cancer susceptibility, and gene therapy for UGT deficiencies.Entities:
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Year: 2004 PMID： 14977861 DOI： 10.1124/dmd.32.3.281
Source DB: PubMed Journal: Drug Metab Dispos ISSN： 0090-9556 Impact factor: 3.922