Literature DB >> 14977082

Clinical relevance of nasal polyps in individuals recruited from a general population-based study.

L Johansson1, A Brämerson, K Holmberg, I Melén, A Akerlund, M Bende.   

Abstract

OBJECTIVE: To compare the clinical presentations of individuals with nasal polyps detected by endoscopy in a general population sample with those of patients with nasal polyp disease seeking medical attention.
MATERIAL AND METHODS: A total of 38 individuals with nasal polyps from a population-based sample were compared with 38 matched controls and a third group consisting of 44 patients who presented to an outpatient clinic with symptoms and diagnosed nasal polyps Upper and lower airway symptoms were registered. Polyp size, peak nasal inspiratory flow (PNIF), olfactory function and health-related quality of life were measured.
RESULTS: Compared with the individuals with nasal polyps in the population sample, patients actively seeking medical care for nasal polyposis experienced more symptoms of nasal blockage and an impaired sense of smell, and had more extensive polyps and reduced PNIF. There were equal frequencies of asthma symptoms in these two groups. Compared with the controls, the individuals with nasal polyps in the population sample had a greater frequency of asthma symptoms and aspirin intolerance and also experienced an impaired sense of smell.
CONCLUSION: Nasal polyps alone, as seen occasionally, are indicative of airway disease involving the upper and lower respiratory tracts.

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Year:  2004        PMID: 14977082     DOI: 10.1080/00016480310016037

Source DB:  PubMed          Journal:  Acta Otolaryngol        ISSN: 0001-6489            Impact factor:   1.494


  4 in total

1.  Histopathological examination of the effects of radiofrequency treatment on mucosa in patients with inferior nasal concha hypertrophy.

Authors:  Mustafa F Sargon; H Hamdi Celik; S Sabri Uslu; O Taşkin Yücel; Cem C Denk; Alper Ceylan
Journal:  Eur Arch Otorhinolaryngol       Date:  2008-06-10       Impact factor: 2.503

2.  Comparison of the effect of endoscopic sinus surgery versus medical therapy on olfaction in nasal polyposis.

Authors:  Mohammad Hossein Baradaranfar; Zeynab Sadat Ahmadi; Mohammad Hossein Dadgarnia; Mohammad Hossein Bemanian; Saeid Atighechi; Ghasem Karimi; Abolhasan Halvani; Nasim Behniafard; Amin Baradaranfar; Tohid Emami Meybodi
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-05-23       Impact factor: 2.503

3.  A family-based genome-wide association study of chronic rhinosinusitis with nasal polyps implicates several genes in the disease pathogenesis.

Authors:  Anton Bohman; Julius Juodakis; Martin Oscarsson; Jonas Bacelis; Mats Bende; Åsa Torinsson Naluai
Journal:  PLoS One       Date:  2017-12-18       Impact factor: 3.240

Review 4.  Epidemiology of chronic rhinosinusitis, selected risk factors, comorbidities, and economic burden.

Authors:  Achim Beule
Journal:  GMS Curr Top Otorhinolaryngol Head Neck Surg       Date:  2015-12-22
  4 in total

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