Literature DB >> 14976960

Serum-stable and long-circulating, PEGylated, pH-sensitive liposomes.

Emmanuelle Roux1, Catherine Passirani, Stefanie Scheffold, Jean-Pierre Benoit, Jean-Christophe Leroux.   

Abstract

pH sensitive liposomes were prepared using a terminally-alkylated copolymer of N-isopropylacrylamide (NIPAM) and methacrylic acid (MAA) and poly(ethylene glycol) phospholipid derivative. The pH-triggered content release was evaluated before and after incubation in serum. Pharmacokinetic and biodistribution profiles of the formulations were established in rats. This study showed that a pH-sensitive, serum-stable and long-circulating liposomal formulation can be produced.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 14976960     DOI： 10.1016/j.jconrel.2003.10.024

Source DB:  PubMed          Journal:  J Control Release        ISSN： 0168-3659            Impact factor:   9.776


  13 in total

1.  Protease-triggered unveiling of bioactive nanoparticles.

Authors:  Todd J Harris; Geoffrey von Maltzahn; Matthew E Lord; Ji-Ho Park; Amit Agrawal; Dal-Hee Min; Michael J Sailor; Sangeeta N Bhatia
Journal:  Small       Date:  2008-09       Impact factor: 13.281

2.  Fluorescence study of lipid bilayer interactions of Eu(III) coordination complexes.

Authors:  Olga K Kutsenko; Valeriya M Trusova; Galyna P Gorbenko; Todor Deligeorgiev; Aleksey Vasilev; Stefka Kaloianova; Nedyalko Lesev
Journal:  J Fluoresc       Date:  2011-02-22       Impact factor: 2.217

3.  Novel graft copolymers enhance in vitro delivery of antisense oligonucleotides in the presence of serum.

Authors:  Lavanya Y Peddada; Nicole K Harris; David I Devore; Charles M Roth
Journal:  J Control Release       Date:  2009-08-20       Impact factor: 9.776

4.  The co-delivery of oxaliplatin abrogates the immunogenic response to PEGylated siRNA-lipoplex.

Authors:  Eman Alaaeldin; Amr S Abu Lila; Naoto Moriyoshi; Hatem A Sarhan; Tatsuhiro Ishida; Khaled A Khaled; Hiroshi Kiwada
Journal:  Pharm Res       Date:  2013-05-15       Impact factor: 4.200

Review 5.  Targeted pharmaceutical nanocarriers for cancer therapy and imaging.

Authors:  Vladimir P Torchilin
Journal:  AAPS J       Date:  2007-05-11       Impact factor: 4.009

6.  Lipid nature and their influence on opening of redox-active liposomes.

Authors:  Martin Loew; Jerimiah C Forsythe; Robin L McCarley
Journal:  Langmuir       Date:  2013-05-22       Impact factor: 3.882

Review 7.  Multifunctional and stimuli-sensitive pharmaceutical nanocarriers.

Authors:  Vladimir Torchilin
Journal:  Eur J Pharm Biopharm       Date:  2008-10-17       Impact factor: 5.571

8.  Delivery of antisense oligonucleotides using poly(alkylene oxide)-poly(propylacrylic acid) graft copolymers in conjunction with cationic liposomes.

Authors:  Lavanya Y Peddada; Olga B Garbuzenko; David I Devore; Tamara Minko; Charles M Roth
Journal:  J Control Release       Date:  2014-09-01       Impact factor: 9.776

9.  Modeling drug-carrier interaction in the drug release from nanocarriers.

Authors:  Like Zeng; Lingling An; Xiaoyi Wu
Journal:  J Drug Deliv       Date:  2011-08-10

10.  Investigating the Intracellular Behaviors of Liposomal Nanohybrids via SERS: Insights into the Influence of Metal Nanoparticles.

Authors:  Dan Zhu; Zhuyuan Wang; Shenfei Zong; Yizhi Zhang; Chen Chen; Ruohu Zhang; Binfeng Yun; Yiping Cui
Journal:  Theranostics       Date:  2018-01-01       Impact factor: 11.556
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.