Literature DB >> 14976730

The production and application of single-chain antibody fragments.

D Blazek1, V Celer.   

Abstract

This review discusses methods for the single-chain antibody fragment ($cFv) generation and scFv expression systems, and describes potential applications of scFv in the therapy of viral diseases and cancer, with emphasis on intracellularly expressed scFvs (intrabodies), application of scFvs in detection and diagnostics, and their use in proteomics.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 14976730     DOI： 10.1007/bf02993480

Source DB:  PubMed          Journal:  Folia Microbiol (Praha)        ISSN： 0015-5632            Impact factor:   2.099


  87 in total

1.  Clinical trials with Pseudomonas exotoxin immunotoxins.

Authors:  L H Pai; I Pastan
Journal:  Curr Top Microbiol Immunol       Date:  1998       Impact factor: 4.291

2.  High level production of soluble single chain antibodies in small-scale Escherichia coli cultures.

Authors:  S M Kipriyanov; G Moldenhauer; M Little
Journal:  J Immunol Methods       Date:  1997-01-15       Impact factor: 2.303

3.  Phage-displayed and soluble mouse scFv fragments neutralize rabies virus.

Authors:  B H Muller; F Lafay; C Demangel; P Perrin; N Tordo; A Flamand; P Lafaye; J L Guesdon
Journal:  J Virol Methods       Date:  1997-09       Impact factor: 2.014

4.  Cloning, expression and functional activities of a single chain antibody fragment directed to fusion protein of respiratory syncytial virus.

Authors:  F Guirakhoo; J Catalan; T Monath; R Weltzin
Journal:  Immunotechnology       Date:  1996-09

5.  Intracellular immunization with cytosolic recombinant antibodies.

Authors:  S Biocca; P Pierandrei-Amaldi; N Campioni; A Cattaneo
Journal:  Biotechnology (N Y)       Date:  1994-04

6.  In situ cytokine therapy: redistribution of clonally expanded T cells.

Authors:  P thor Straten; P Guldberg; D Schrama; M H Andersen; U Moerch; T Seremet; C Siedel; R A Reisfeld; J C Becker
Journal:  Eur J Immunol       Date:  2001-01       Impact factor: 5.532

7.  Intracellular expression of single-chain variable fragments to inhibit early stages of the viral life cycle by targeting human immunodeficiency virus type 1 integrase.

Authors:  P Levy-Mintz; L Duan; H Zhang; B Hu; G Dornadula; M Zhu; J Kulkosky; D Bizub-Bender; A M Skalka; R J Pomerantz
Journal:  J Virol       Date:  1996-12       Impact factor: 5.103

8.  Recombinant antibody Fab against the hypervariable region 1 of hepatitis C virus blocks the virus adsorption to susceptible cells in vitro.

Authors:  Yi-Hua Zhou; Masataka Takekoshi; Fumiko Maeda; Seiji Ihara; Mariko Esumi
Journal:  Antiviral Res       Date:  2002-10       Impact factor: 5.970

9.  A COS-cell-based system for rapid production and quantification of scFv::IgC kappa antibody fragments.

Authors:  R Ridder; S Geisse; B Kleuser; P Kawalleck; H Gram
Journal:  Gene       Date:  1995-12-12       Impact factor: 3.688

10.  Functional properties of a monoclonal antibody inhibiting the hepatitis C virus RNA-dependent RNA polymerase.

Authors:  Darius Moradpour; Elke Bieck; Thomas Hügle; Winfried Wels; Jim Zhen Wu; Zhi Hong; Hubert E Blum; Ralf Bartenschlager
Journal:  J Biol Chem       Date:  2001-10-18       Impact factor: 5.157
View more
  6 in total

1.  Trans-splicing into highly abundant albumin transcripts for production of therapeutic proteins in vivo.

Authors:  Jun Wang; S Gary Mansfield; Colette A Cote; Ping Du Jiang; Ke Weng; Marcelo J A Amar; Bryan H Brewer; Alan T Remaley; Gerard J McGarrity; Mariano A Garcia-Blanco; M Puttaraju
Journal:  Mol Ther       Date:  2008-12-09       Impact factor: 11.454

2.  Construction, expression and functional analysis of anti-B7-H4- scFv-CH3 recombinant antibody.

Authors:  Hongshuai Ji; Jinrui Guo; Ying Yang; Chaochao Xu; Weiping Mao
Journal:  J Biosci       Date:  2018-09       Impact factor: 1.826

3.  Phage display on the base of filamentous bacteriophages: application for recombinant antibodies selection.

Authors:  N V Tikunova; V V Morozova
Journal:  Acta Naturae       Date:  2009-10       Impact factor: 1.845

4.  ---Successful Application of Whole Cell Panning for Isolation of Phage Antibody Fragments Specific to Differentiated Gastric Cancer Cells.

Authors:  Sepideh Nikfarjam; Mohammad Reza Tohidkia; Tayebeh Mehdipour; Ramin Soleimani; Ali Akbar Rahim Rahimi; Mohammad Nouri
Journal:  Adv Pharm Bull       Date:  2019-10-24

5.  Generation of recombinant antibodies to rat GABAA receptor subunits by affinity selection on synthetic peptides.

Authors:  Sujatha P Koduvayur; Hélène A Gussin; Rajni Parthasarathy; Zengping Hao; Brian K Kay; David R Pepperberg
Journal:  PLoS One       Date:  2014-02-19       Impact factor: 3.240

Review 6.  Phage Display Derived Monoclonal Antibodies: From Bench to Bedside.

Authors:  Mohamed A Alfaleh; Hashem O Alsaab; Ahmad Bakur Mahmoud; Almohanad A Alkayyal; Martina L Jones; Stephen M Mahler; Anwar M Hashem
Journal:  Front Immunol       Date:  2020-08-28       Impact factor: 7.561
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.