Literature DB >> 14976030

TANDEM: matching proteins with tandem mass spectra.

Robertson Craig1, Ronald C Beavis.   

Abstract

SUMMARY: Tandem mass spectra obtained from fragmenting peptide ions contain some peptide sequence specific information, but often there is not enough information to sequence the original peptide completely. Several proprietary software applications have been developed to attempt to match the spectra with a list of protein sequences that may contain the sequence of the peptide. The application TANDEM was written to provide the proteomics research community with a set of components that can be used to test new methods and algorithms for performing this type of sequence-to-data matching. AVAILABILITY: The source code and binaries for this software are available at http://www.proteome.ca/opensource.html, for Windows, Linux and Macintosh OSX. The source code is made available under the Artistic License, from the authors.

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Year:  2004        PMID: 14976030     DOI: 10.1093/bioinformatics/bth092

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  958 in total

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7.  A ranking-based scoring function for peptide-spectrum matches.

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8.  Tiered Human Integrated Sequence Search Databases for Shotgun Proteomics.

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