Literature DB >> 14975235

Routes to transplant tolerance versus rejection; the role of cytokines.

Patrick T Walsh1, Terry B Strom, Laurence A Turka.   

Abstract

The alloimmune response can be divided into specific junctures where critical decisions between tolerance and immunity are made which define the outcome of the transplant. At these "decision nodes" various cytokines direct alloresponsive T cells to develop either a proinflammatory response aimed at graft destruction or an immunoregulatory response facilitating graft acceptance. This review will focus on the role of these cytokines in influencing the progression of an alloimmune response leading ultimately to either allograft survival or rejection.

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Year:  2004        PMID： 14975235      PMCID： PMC3807577          DOI： 10.1016/s1074-7613(04)00024-x

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  91 in total

1.  Quantifying the frequency of alloreactive T cells in vivo: new answers to an old question.

Authors:  E J Suchin; P B Langmuir; E Palmer; M H Sayegh; A D Wells; L A Turka
Journal:  J Immunol       Date:  2001-01-15       Impact factor: 5.422

2.  Impaired alloantigen-mediated T cell apoptosis and failure to induce long-term allograft survival in IL-2-deficient mice.

Authors:  Z Dai; B T Konieczny; F K Baddoura; F G Lakkis
Journal:  J Immunol       Date:  1998-08-15       Impact factor: 5.422

3.  Indirect T cell allorecognition and alloantibody-mediated rejection of MHC class I-disparate heart grafts.

Authors:  G J Pettigrew; E Lovegrove; J A Bradley; J Maclean; E M Bolton
Journal:  J Immunol       Date:  1998-08-01       Impact factor: 5.422

4.  IL-2 and IL-4 double knockout mice reject islet allografts: a role for novel T cell growth factors in allograft rejection.

Authors:  X C Li; P Roy-Chaudhury; W W Hancock; R Manfro; M S Zand; Y Li; X X Zheng; P W Nickerson; J Steiger; T R Malek; T B Strom
Journal:  J Immunol       Date:  1998-07-15       Impact factor: 5.422

5.  On histocompatibility barriers, Th1 to Th2 immune deviation, and the nature of the allograft responses.

Authors:  X C Li; M S Zand; Y Li; X X Zheng; T B Strom
Journal:  J Immunol       Date:  1998-09-01       Impact factor: 5.422

Review 6.  Dendritic cells and the control of immunity.

Authors:  J Banchereau; R M Steinman
Journal:  Nature       Date:  1998-03-19       Impact factor: 49.962

7.  Cytokine-induced survival of activated T cells in vitro and in vivo.

Authors:  A T Vella; S Dow; T A Potter; J Kappler; P Marrack
Journal:  Proc Natl Acad Sci U S A       Date:  1998-03-31       Impact factor: 11.205

8.  Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis.

Authors:  Y Refaeli; L Van Parijs; C A London; J Tschopp; A K Abbas
Journal:  Immunity       Date:  1998-05       Impact factor: 31.745

Review 9.  The role of different subsets of T regulatory cells in controlling autoimmunity.

Authors:  M G Roncarolo; M K Levings
Journal:  Curr Opin Immunol       Date:  2000-12       Impact factor: 7.486

10.  Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells.

Authors:  H Jonuleit; E Schmitt; G Schuler; J Knop; A H Enk
Journal:  J Exp Med       Date:  2000-11-06       Impact factor: 14.307
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  20 in total

Review 1.  Tregs and transplantation tolerance.

Authors:  Patrick T Walsh; Devon K Taylor; Laurence A Turka
Journal:  J Clin Invest       Date:  2004-11       Impact factor: 14.808

2.  Surgical angiogenesis modifies the cellular environment of nerve allografts in a rat sciatic nerve defect model.

Authors:  Tiam M Saffari; Amr Badreldin; Femke Mathot; Leila Bagheri; Allen T Bishop; Andre J van Wijnen; Alexander Y Shin
Journal:  Gene       Date:  2020-04-27       Impact factor: 3.688

3.  Impaired immune responses and prolonged allograft survival in Sly1 mutant mice.

Authors:  Sandra Beer; Tanja Scheikl; Bernhard Reis; Norbert Hüser; Klaus Pfeffer; Bernhard Holzmann
Journal:  Mol Cell Biol       Date:  2005-11       Impact factor: 4.272

Review 4.  Adaptive immune cell responses as therapeutic targets in antibody-mediated organ rejection.

Authors:  Kevin Louis; Camila Macedo; Carmen Lefaucheur; Diana Metes
Journal:  Trends Mol Med       Date:  2022-01-29       Impact factor: 11.951

5.  FasL expression in hepatic antigen-presenting cells and phagocytosis of apoptotic T cells by FasL+ Kupffer cells are indicators of rejection activity in human liver allografts.

Authors:  Aya Miyagawa-Hayashino; Tatsuaki Tsuruyama; Hiroto Egawa; Hironori Haga; Hiromi Sakashita; Tomoko Okuno; Shinya Toyokuni; Keiji Tamaki; Hirohiko Yamabe; Toshiaki Manabe; Shinji Uemoto
Journal:  Am J Pathol       Date:  2007-09-06       Impact factor: 4.307

6.  Effects of nilotinib on regulatory T cells: the dose matters.

Authors:  Fei Fei; Yingzhe Yu; Anita Schmitt; Markus T Rojewski; Baoan Chen; Jochen Greiner; Marlies Götz; Donald Bunjes; Michael Schmitt
Journal:  Mol Cancer       Date:  2010-01-29       Impact factor: 27.401

7.  Dasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation.

Authors:  Andrew E Schade; Gary L Schieven; Robert Townsend; Anna M Jankowska; Vojkan Susulic; Rosemary Zhang; Hadrian Szpurka; Jaroslaw P Maciejewski
Journal:  Blood       Date:  2007-10-25       Impact factor: 22.113

Review 8.  Controlling the burn and fueling the fire: defining the role for the alarmin interleukin-33 in alloimmunity.

Authors:  Quan Liu; Heth R Turnquist
Journal:  Curr Opin Organ Transplant       Date:  2016-02       Impact factor: 2.640

9.  IL-21 is an antitolerogenic cytokine of the late-phase alloimmune response.

Authors:  Alessandra Petrelli; Michele Carvello; Andrea Vergani; Kang Mi Lee; Sara Tezza; Ming Du; Sonja Kleffel; Liu Chengwen; Bechara G Mfarrej; Patrick Hwu; Antonio Secchi; Warren J Leonard; Deborah Young; Mohamed H Sayegh; James F Markmann; Allan J Zajac; Paolo Fiorina
Journal:  Diabetes       Date:  2011-10-19       Impact factor: 9.461

10.  T-bet+CD27+CD21- B cells poised for plasma cell differentiation during antibody-mediated rejection of kidney transplants.

Authors:  Kevin Louis; Elodie Bailly; Camila Macedo; Louis Lau; Bala Ramaswami; Alexander Chang; Uma Chandran; Douglas Landsittel; Xinyan Gu; Geetha Chalasani; Adriana Zeevi; Parmjeet Randhawa; Harinder Singh; Carmen Lefaucheur; Diana Metes
Journal:  JCI Insight       Date:  2021-06-22
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