| Literature DB >> 14972539 |
Gamze Karaca1, Jonathan Anobile, Danielle Downs, Joan Burnside, Carl J Schmidt.
Abstract
Herpesvirus of turkeys (HVT) provides an economically important live vaccine for prevention of Marek's disease (MD) of chickens. MD, characterized by both immunosuppression and T-cell lymphoma, is caused by another herpesvirus termed Marek's disease virus (MDV). Microarrays were used to investigate the response of chicken embryonic fibroblasts (CEF) to infection with HVT. Genes responding to HVT infection include several induced by interferon along with others modulating signal transduction, transcription, scaffolding proteins, and the cytoskeleton. Results are compared with earlier studies examining the responses of CEF cells to infection with MDV.Entities:
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Year: 2004 PMID: 14972539 DOI: 10.1016/j.virol.2003.09.025
Source DB: PubMed Journal: Virology ISSN: 0042-6822 Impact factor: 3.616