Literature DB >> 1497155

Clinical predictors of bacterial versus aseptic meningitis in childhood.

C Walsh-Kelly1, D B Nelson, D S Smith, J D Losek, M Melzer-Lange, H M Hennes, P W Glaeser.   

Abstract

STUDY
OBJECTIVE: To assess the reliability of meningeal signs and other physical findings in predicting bacterial and aseptic meningitis at various ages.
DESIGN: Children requiring lumbar puncture were evaluated prospectively for meningeal signs and other physical parameters before lumbar puncture.
SETTING: Emergency department of Children's Hospital of Wisconsin. PARTICIPANTS: One hundred seventy-two children, aged 1 week to 17 years, with meningitis (53 bacterial and 119 aseptic).
MEASUREMENTS AND MAIN RESULTS: Nuchal rigidity was present in 27% of infants aged 0 to 6 months with bacterial meningitis versus 95% of patients 19 months or older (P = .0001). Three percent of infants 0 to 6 months old with aseptic meningitis had nuchal rigidity versus 79% of patients 19 months or older (P = .0005). Seventy-two percent of infants 12 months of age or younger with bacterial meningitis has at least one positive meningeal sign versus 17% of infants with aseptic meningitis (P = .0001). Eighty-five percent of children older than 12 months with meningitis had at least one positive meningeal sign, 93% with bacterial meningitis, and 82% with aseptic meningitis.
CONCLUSION: Despite a lack of meningeal signs, a high index of suspicion for meningitis is essential when evaluating the febrile infant 12 months of age or younger.

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Year:  1992        PMID: 1497155     DOI: 10.1016/s0196-0644(05)82926-9

Source DB:  PubMed          Journal:  Ann Emerg Med        ISSN: 0196-0644            Impact factor:   5.721


  1 in total

1.  How to differentiate bacterial from viral meningitis.

Authors:  Werner Zimmerli
Journal:  Intensive Care Med       Date:  2005-10-22       Impact factor: 17.440

  1 in total

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