OBJECTIVES: To investigate the components of adolescent diet that may influence risk of breast cancer as an adult. METHODS: Retrospective cohort study among 47,355 participants in the Nurses Health Study II who answered a 131-item food frequency questionnaire about diet during high school. Cox proportional hazards regression was used to estimate relative risks and 95% confidence intervals among incident cases of breast cancer between 1989 (inception of the study) and 1998 (when high school diet was assessed). RESULTS: Intakes of fat and fiber were not significantly related to risk of breast cancer in multivariate analysis, but increased intake of vegetable fat ( Q (5) versus Q (1) multivariate RR = 0.58, 95% CI (0.38-0.86); test for trend p = 0.005) and vitamin E ( Q (5) versus Q (1) multivariate RR = 0.61, 95% CI (0.42-0.89); test for trend p = 0.003) were associated with a lower risk. A higher dietary glycemic index ( Q (5) versus Q (1) multivariate RR = 1.47, 95% CI (1.04-2.08); test for trend p = 0.01) was associated with increased risk of breast cancer. CONCLUSIONS: The apparent protective effects of vegetable fat and vitamin E and adverse effect of high glycemic foods on risk of breast cancer need confirmation in prospective analyses.
OBJECTIVES: To investigate the components of adolescent diet that may influence risk of breast cancer as an adult. METHODS: Retrospective cohort study among 47,355 participants in the Nurses Health Study II who answered a 131-item food frequency questionnaire about diet during high school. Cox proportional hazards regression was used to estimate relative risks and 95% confidence intervals among incident cases of breast cancer between 1989 (inception of the study) and 1998 (when high school diet was assessed). RESULTS: Intakes of fat and fiber were not significantly related to risk of breast cancer in multivariate analysis, but increased intake of vegetable fat ( Q (5) versus Q (1) multivariate RR = 0.58, 95% CI (0.38-0.86); test for trend p = 0.005) and vitamin E ( Q (5) versus Q (1) multivariate RR = 0.61, 95% CI (0.42-0.89); test for trend p = 0.003) were associated with a lower risk. A higher dietary glycemic index ( Q (5) versus Q (1) multivariate RR = 1.47, 95% CI (1.04-2.08); test for trend p = 0.01) was associated with increased risk of breast cancer. CONCLUSIONS: The apparent protective effects of vegetable fat and vitamin E and adverse effect of high glycemic foods on risk of breast cancer need confirmation in prospective analyses.
Authors: Elizabeth H Ruder; Anne C M Thiébaut; Frances E Thompson; Nancy Potischman; Amy F Subar; Yikyung Park; Barry I Graubard; Albert R Hollenbeck; Amanda J Cross Journal: Am J Clin Nutr Date: 2011-11-09 Impact factor: 7.045
Authors: Joanne F Dorgan; Lea Liu; Catherine Klifa; Nola Hylton; John A Shepherd; Frank Z Stanczyk; Linda G Snetselaar; Linda Van Horn; Victor J Stevens; Alan Robson; Peter O Kwiterovich; Norman L Lasser; John H Himes; Kelley Pettee Gabriel; Andrea Kriska; Elizabeth H Ruder; Carolyn Y Fang; Bruce A Barton Journal: Cancer Epidemiol Biomarkers Prev Date: 2010-05-25 Impact factor: 4.254
Authors: Xuefen Su; Graham A Colditz; Laura C Collins; Heather J Baer; Laura A Sampson; Walter C Willett; Catherine S Berkey; Stuart J Schnitt; James L Connolly; Bernard A Rosner; Rulla M Tamimi Journal: Breast Cancer Res Treat Date: 2012-05-24 Impact factor: 4.872
Authors: Catherine S Berkey; Walter C Willett; Rulla M Tamimi; Bernard Rosner; A Lindsay Frazier; Graham A Colditz Journal: Breast Cancer Res Treat Date: 2013-09-17 Impact factor: 4.872
Authors: Eleni Linos; Walter C Willett; Eunyoung Cho; Graham Colditz; Lindsay A Frazier Journal: Cancer Epidemiol Biomarkers Prev Date: 2008-07-31 Impact factor: 4.254
Authors: Linda T Hiraki; Kassandra L Munger; Karen H Costenbader; Elizabeth W Karlson Journal: Arthritis Care Res (Hoboken) Date: 2012-12 Impact factor: 4.794
Authors: Patrick T Bradshaw; Sharon K Sagiv; Geoffrey C Kabat; Jessie A Satia; Julie A Britton; Susan L Teitelbaum; Alfred I Neugut; Marilie D Gammon Journal: Cancer Causes Control Date: 2009-04-23 Impact factor: 2.506
Authors: Jorge E Chavarro; Bernard A Rosner; Laura Sampson; Carol Willey; Paula Tocco; Walter C Willett; Wm Cameron Chumlea; Karin B Michels Journal: Am J Epidemiol Date: 2009-11-18 Impact factor: 4.897