OBJECTIVE: To describe the national trends in lung cancer incidence among young adults and the relationship to adolescent smoking. METHODS: Between 1954 and 1998, a total of 1108 non-carcinoid lung cancers were reported to the Cancer Registry of Norway in individuals aged 20-44 years. Temporal variations were studied in age and sex specific rates, in age-adjusted rates, and by means of age-period-cohort modelling. The association between cancer incidence and smoking prevalence was evaluated. RESULTS: The lung cancer incidence rate among women aged 40-44 in Norway continued to increase into the most recent time interval (1994-1998) whereas the rate among men aged 40-44 was essentially constant after 1970. Consequently, lung cancer incidence rates converged among male and female young adults. Lung cancer incidence rates at age 40-44 were highly correlated with smoking prevalence at age 15-19 in males ( r = 0.88) and females ( r = 0.82) within the same birth cohort. CONCLUSIONS: The lung cancer incidence rate in young Norwegian women now equals that of men. The risk at age 40-44 was closely associated with teenage smoking, indicating that duration and age of onset are important.
OBJECTIVE: To describe the national trends in lung cancer incidence among young adults and the relationship to adolescent smoking. METHODS: Between 1954 and 1998, a total of 1108 non-carcinoid lung cancers were reported to the Cancer Registry of Norway in individuals aged 20-44 years. Temporal variations were studied in age and sex specific rates, in age-adjusted rates, and by means of age-period-cohort modelling. The association between cancer incidence and smoking prevalence was evaluated. RESULTS: The lung cancer incidence rate among women aged 40-44 in Norway continued to increase into the most recent time interval (1994-1998) whereas the rate among men aged 40-44 was essentially constant after 1970. Consequently, lung cancer incidence rates converged among male and female young adults. Lung cancer incidence rates at age 40-44 were highly correlated with smoking prevalence at age 15-19 in males ( r = 0.88) and females ( r = 0.82) within the same birth cohort. CONCLUSIONS: The lung cancer incidence rate in young Norwegian women now equals that of men. The risk at age 40-44 was closely associated with teenage smoking, indicating that duration and age of onset are important.
Authors: Li-Shiun Chen; Eric O Johnson; Naomi Breslau; Dorothy Hatsukami; Nancy L Saccone; Richard A Grucza; Jen C Wang; Anthony L Hinrichs; Louis Fox; Alison M Goate; John P Rice; Laura J Bierut Journal: Addiction Date: 2009-10 Impact factor: 6.526
Authors: Louise A Hertsgaard; Karen Hanson; Stephen S Hecht; Bruce R Lindgren; Xianghua Luo; Steven G Carmella; William T Riley; Emily B Zylla; Sharon E Murphy; Dorothy K Hatsukami Journal: Cancer Epidemiol Biomarkers Prev Date: 2008-12 Impact factor: 4.254