| Literature DB >> 14970698 |
L B Madsen1, A H Petersen, V H Nielsen, P H Nissen, M Dunø, L Krejci, C Bendixen, B Thomsen.
Abstract
The porcine COL10A1 gene, encoding the alpha1(X) chain of type X collagen, has been sequenced. The gene structure is evolutionarily conserved, consisting of three exons and two introns spanning 7100 bp. Linkage mapping localized the gene to chromosome 1, which is in agreement with human-pig homology maps. Furthermore, protein structure comparison of the functionally important carboxyl domain between species revealed that amino acid changes were few and mainly situated in loop regions. Copyright 2003 S. Karger AG, BaselEntities:
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Year: 2003 PMID： 14970698 DOI： 10.1159/000075744
Source DB: PubMed Journal: Cytogenet Genome Res ISSN： 1424-8581 Impact factor: 1.636