Literature DB >> 14970517

Recombinant immunotoxins in the treatment of cancer.

Ira Pastan1, Richard Beers, Tapan K Bera.   

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Year:  2004        PMID： 14970517     DOI： 10.1385/1-59259-666-5:503

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


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  57 in total

1.  Rational design of low immunogenic anti CD25 recombinant immunotoxin for T cell malignancies by elimination of T cell epitopes in PE38.

Authors:  Ronit Mazor; Gilad Kaplan; Dong Park; Youjin Jang; Fred Lee; Robert Kreitman; Ira Pastan
Journal:  Cell Immunol       Date:  2017-01-05       Impact factor: 4.868

2.  Differential cellular internalization of anti-CD19 and -CD22 immunotoxins results in different cytotoxic activity.

Authors:  Xing Du; Richard Beers; David J Fitzgerald; Ira Pastan
Journal:  Cancer Res       Date:  2008-08-01       Impact factor: 12.701

3.  Site-Specific PEGylation of Anti-Mesothelin Recombinant Immunotoxins Increases Half-life and Antitumor Activity.

Authors:  Zeliang Zheng; Ryuhei Okada; Hisataka Kobayashi; Tadanobu Nagaya; Junxia Wei; Qi Zhou; Fred Lee; Tapan K Bera; Yun Gao; William Kuhlman; Chin-Hsien Tai; Ira Pastan
Journal:  Mol Cancer Ther       Date:  2019-12-23       Impact factor: 6.261

4.  Cytotoxicity of the anti-CD22 immunotoxin HA22 (CAT-8015) against paediatric acute lymphoblastic leukaemia.

Authors:  Francis Mussai; Dario Campana; Deepa Bhojwani; Maryalice Stetler-Stevenson; Seth M Steinberg; Alan S Wayne; Ira Pastan
Journal:  Br J Haematol       Date:  2010-06-07       Impact factor: 6.998

5.  Elimination of murine and human T-cell epitopes in recombinant immunotoxin eliminates neutralizing and anti-drug antibodies in vivo.

Authors:  Ronit Mazor; Devorah Crown; Selamawit Addissie; Youjin Jang; Gilad Kaplan; Ira Pastan
Journal:  Cell Mol Immunol       Date:  2015-10-19       Impact factor: 11.530

6.  Expression of POTE protein in human testis detected by novel monoclonal antibodies.

Authors:  Tomoko Ise; Sudipto Das; Satoshi Nagata; Hiroshi Maeda; Yoomi Lee; Masanori Onda; Miriam R Anver; Tapan K Bera; Ira Pastan
Journal:  Biochem Biophys Res Commun       Date:  2007-11-09       Impact factor: 3.575

7.  Eradication of tumor colonization and invasion by a B cell-specific immunotoxin in a murine model for human primary intraocular lymphoma.

Authors:  Zhuqing Li; Sankaranarayana P Mahesh; De Fen Shen; Baoying Liu; Willie O Siu; Frank S Hwang; Qing-Chen Wang; Chi-Chao Chan; Ira Pastan; Robert B Nussenblatt
Journal:  Cancer Res       Date:  2006-11-01       Impact factor: 12.701

8.  In vitro and in vivo antitumor effects of the recombinant immunotoxin IL6(T23)-PE38KDEL in multiple myeloma.

Authors:  DE-Jun Guo; Jia-Shan Han; Yan-Song Li; Zeng-Shan Liu; Shi-Ying Lu; Hong-Lin Ren
Journal:  Oncol Lett       Date:  2012-05-25       Impact factor: 2.967

9.  Reduced Shedding of Surface Mesothelin Improves Efficacy of Mesothelin-Targeting Recombinant Immunotoxins.

Authors:  Prince Awuah; Tapan K Bera; Messan Folivi; Oleg Chertov; Ira Pastan
Journal:  Mol Cancer Ther       Date:  2016-05-18       Impact factor: 6.261

10.  A modified form of diphthamide causes immunotoxin resistance in a lymphoma cell line with a deletion of the WDR85 gene.

Authors:  Hui Wei; Tapan K Bera; Alan S Wayne; Laiman Xiang; Simona Colantonio; Oleg Chertov; Ira Pastan
Journal:  J Biol Chem       Date:  2013-03-13       Impact factor: 5.157
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