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Literature DB >> 14968912

Ciliary neurotrophic factor: a role in obesity?

Abstract

Ciliary neurotrophic factor (CNTF) is a neurocytokine expressed by glial cells in peripheral nerves and the central nervous system. CNTF is generally recognized for its function in support and survival of non-neuronal and neuronal cell types. Following a serendipitous finding, CNTF was recently acknowledged for its potential role in the control of obesity.

Entities: Disease Gene

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Year: 2003 PMID： 14968912 DOI： 10.1301/nr.2003.dec.423-426

Source DB: PubMed Journal: Nutr Rev ISSN： 0029-6643 Impact factor: 7.110

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Cited

9 in total

Review 1. The ever-expanding myokinome: discovery challenges and therapeutic implications.

Authors: Martin Whitham; Mark A Febbraio
Journal: Nat Rev Drug Discov Date: 2016-09-12 Impact factor: 84.694

2. Treatment of type 2 diabetes with the designer cytokine IC7Fc.

Authors: Maria Findeisen; Tamara L Allen; Darren C Henstridge; Helene Kammoun; Amanda E Brandon; Laurie L Baggio; Kevin I Watt; Martin Pal; Lena Cron; Emma Estevez; Christine Yang; Greg M Kowalski; Liam O'Reilly; Casey Egan; Emily Sun; Le May Thai; Guy Krippner; Timothy E Adams; Robert S Lee; Joachim Grötzinger; Christoph Garbers; Steve Risis; Michael J Kraakman; Natalie A Mellet; James Sligar; Erica T Kimber; Richard L Young; Michael A Cowley; Clinton R Bruce; Peter J Meikle; Paul A Baldock; Paul Gregorevic; Trevor J Biden; Gregory J Cooney; Damien J Keating; Daniel J Drucker; Stefan Rose-John; Mark A Febbraio
Journal: Nature Date: 2019-09-25 Impact factor: 49.962

3. Ciliary neurotrophic factor cell-based delivery prevents synaptic impairment and improves memory in mouse models of Alzheimer's disease.

Authors: Pierre Garcia; Ihsen Youssef; Jo K Utvik; Sabrina Florent-Béchard; Vanassa Barthélémy; Catherine Malaplate-Armand; Badreddine Kriem; Christophe Stenger; Violette Koziel; Jean-Luc Olivier; Marie-Christine Escanye; Marine Hanse; Ahmad Allouche; Cédric Desbène; Frances T Yen; Rolf Bjerkvig; Thierry Oster; Simone P Niclou; Thierry Pillot
Journal: J Neurosci Date: 2010-06-02 Impact factor: 6.167

4. Ciliary neurotrophic factor, cardiotrophin-like cytokine, and neuropoietin share a conserved binding site on the ciliary neurotrophic factor receptor alpha chain.

Authors: François Rousseau; Sylvie Chevalier; Catherine Guillet; Elisa Ravon; Caroline Diveu; Josy Froger; Fabien Barbier; Linda Grimaud; Hugues Gascan
Journal: J Biol Chem Date: 2008-08-26 Impact factor: 5.157

5. Increased ciliary neurotrophic factor in blood serum and lacrimal fluid as a potential biomarkers of focal epilepsy.

Authors: Alexander Shpak; Alla Guekht; Tatiana Druzhkova; Flora Rider; Anna Gudkova; Natalia Gulyaeva
Journal: Neurol Sci Date: 2021-05-24 Impact factor: 3.307

6. Dendrobium alkaloids prevent Aβ_25-35-induced neuronal and synaptic loss via promoting neurotrophic factors expression in mice.

Authors: Jing Nie; Yong Tian; Yu Zhang; Yan-Liu Lu; Li-Sheng Li; Jing-Shan Shi
Journal: PeerJ Date: 2016-12-13 Impact factor: 2.984

Ciliary neurotrophic factor: a role in obesity?

Review 1. The ever-expanding myokinome: discovery challenges and therapeutic implications.

2. Treatment of type 2 diabetes with the designer cytokine IC7Fc.

3. Ciliary neurotrophic factor cell-based delivery prevents synaptic impairment and improves memory in mouse models of Alzheimer's disease.

4. Ciliary neurotrophic factor, cardiotrophin-like cytokine, and neuropoietin share a conserved binding site on the ciliary neurotrophic factor receptor alpha chain.

5. Increased ciliary neurotrophic factor in blood serum and lacrimal fluid as a potential biomarkers of focal epilepsy.

6. Dendrobium alkaloids prevent Aβ_25-35-induced neuronal and synaptic loss via promoting neurotrophic factors expression in mice.

Review 7. New insights into IL-6 family cytokines in metabolism, hepatology and gastroenterology.

Review 8. Upregulation of Neuronal Rheb(S16H) for Hippocampal Protection in the Adult Brain.

9. Extensive serum biomarker analysis in the prethrombotic state of recurrent spontaneous abortion.

Ciliary neurotrophic factor: a role in obesity?

Review 1. The ever-expanding myokinome: discovery challenges and therapeutic implications.

2. Treatment of type 2 diabetes with the designer cytokine IC7Fc.

3. Ciliary neurotrophic factor cell-based delivery prevents synaptic impairment and improves memory in mouse models of Alzheimer's disease.

4. Ciliary neurotrophic factor, cardiotrophin-like cytokine, and neuropoietin share a conserved binding site on the ciliary neurotrophic factor receptor alpha chain.

5. Increased ciliary neurotrophic factor in blood serum and lacrimal fluid as a potential biomarkers of focal epilepsy.

6. Dendrobium alkaloids prevent Aβ25-35-induced neuronal and synaptic loss via promoting neurotrophic factors expression in mice.

Review 7. New insights into IL-6 family cytokines in metabolism, hepatology and gastroenterology.

Review 8. Upregulation of Neuronal Rheb(S16H) for Hippocampal Protection in the Adult Brain.

9. Extensive serum biomarker analysis in the prethrombotic state of recurrent spontaneous abortion.

6. Dendrobium alkaloids prevent Aβ_25-35-induced neuronal and synaptic loss via promoting neurotrophic factors expression in mice.