Literature DB >> 14966

Phosphoglycolate phosphatase in human erythrocytes.

J A Badwey.   

Abstract

Human erythrocytes were found to contain an enzyme capable of dephosphorylating phosphoglycolate. The rates of hydrolysis of 14 other metabolites by the enzyme preparation were less than 6% of the rate with phosphoglycolate. The pH optimum is in the range of 6 to 7 and the Km for phosphoglycolate is 0.76 mM. The molecular weight appears to be about 79,000. Such an activity has previously been reported only for plant cells.

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Year:  1977        PMID： 14966

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  9 in total

1.  Model of 2,3-bisphosphoglycerate metabolism in the human erythrocyte based on detailed enzyme kinetic equations: in vivo kinetic characterization of 2,3-bisphosphoglycerate synthase/phosphatase using 13C and 31P NMR.

Authors:  P J Mulquiney; W A Bubb; P W Kuchel
Journal:  Biochem J       Date:  1999-09-15       Impact factor: 3.857

2.  Glycolate and 2-phosphoglycolate content of tissues measured by ion chromatography coupled to mass spectrometry.

Authors:  John Knight; Mark Hinsdale; Ross Holmes
Journal:  Anal Biochem       Date:  2011-10-29       Impact factor: 3.365

3.  Additional data on PGP genetic transmission in family groups.

Authors:  B Caeiro; T A Varela
Journal:  Z Rechtsmed       Date:  1982

4.  Partial purification and characterization of human erythrocyte phosphoglycollate phosphatase.

Authors:  R Zecher; H U Wolf
Journal:  Biochem J       Date:  1980-10-01       Impact factor: 3.857

5.  Human phosphoglycolate phosphatase (PGP) E.C. 3.1.3.18: linkage analysis.

Authors:  G Siebert; A Amorim; J Kömpf
Journal:  Hum Genet       Date:  1980       Impact factor: 4.132

6.  Population, formal genetics, and linkage relations of the phosphoglycolate phosphatase (PGP)--E.C.3.1.3.18.

Authors:  W Brink; M P Baur; C Rittner
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

7.  An essential developmental function for murine phosphoglycolate phosphatase in safeguarding cell proliferation.

Authors:  Gabriela Segerer; Kerstin Hadamek; Matthias Zundler; Agnes Fekete; Annegrit Seifried; Martin J Mueller; Frank Koentgen; Manfred Gessler; Elisabeth Jeanclos; Antje Gohla
Journal:  Sci Rep       Date:  2016-10-12       Impact factor: 4.379

8.  Phosphoglycolate has profound metabolic effects but most likely no role in a metabolic DNA response in cancer cell lines.

Authors:  Isabelle Gerin; Marina Bury; Francesca Baldin; Julie Graff; Emile Van Schaftingen; Guido T Bommer
Journal:  Biochem J       Date:  2019-02-19       Impact factor: 3.857

Review 9.  New Mammalian Glycerol-3-Phosphate Phosphatase: Role in β-Cell, Liver and Adipocyte Metabolism.

Authors:  Elite Possik; Anfal Al-Mass; Marie-Line Peyot; Rasheed Ahmad; Fahd Al-Mulla; S R Murthy Madiraju; Marc Prentki
Journal:  Front Endocrinol (Lausanne)       Date:  2021-07-13       Impact factor: 5.555
  9 in total

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