Literature DB >> 14964448

Hormone use and abuse: what is the difference between hormones as fountain of youth and doping in sports?

A J van der Lely1.   

Abstract

GH can induce changes in body composition that are considered to be advantageous to aging subjects especially. However, there are no results indicating that the use of GH during aging should be advocated, because of the lack of any proven efficacy for whatever parameter. Also, data indicate that calorie restriction can extend life spans by altering the rate of decline in reserve capacity as well as by reducing the cumulative exposure to GH. Moreover, animal data suggest that lower GH actions are positively correlated with longevity. The abuse of GH by sportsmen is based on the belief that it has potent anabolic effects, while it is difficult to detect the abuse. Again, this supposed efficacy cannot be supported by any scientific data.

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Year:  2003        PMID: 14964448     DOI: 10.1007/BF03345246

Source DB:  PubMed          Journal:  J Endocrinol Invest        ISSN: 0391-4097            Impact factor:   4.256


  66 in total

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10.  Dietary calorie restriction in the Emory mouse: effects on lifespan, eye lens cataract prevalence and progression, levels of ascorbate, glutathione, glucose, and glycohemoglobin, tail collagen breaktime, DNA and RNA oxidation, skin integrity, fecundity, and cancer.

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Journal:  Mech Ageing Dev       Date:  1995-03-31       Impact factor: 5.432

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  1 in total

Review 1.  [Lifestyle drugs in medicine].

Authors:  Wolfgang Harth; Kurt Seikowski; Barbara Hermes; Uwe Gieler
Journal:  Wien Med Wochenschr       Date:  2008
  1 in total

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