Literature DB >> 14964430

Antiproliferative effects of abietane diterpenoids isolated from Hyptis martiusii Benth (Labiatae).

L V Costa-Lotufo1, E C C Araújo, M A S Lima, M E A Moraes, C Pessoa, E R Silviera, M O Moraes.   

Abstract

Two abietane diterpenes were isolated from a hexane extract of Hyptis martiusii roots and identified as carnasol 11,14-dihidroxy-8,11,13-abietatrien-7-one. These compounds were tested for their antiproliferative effects on tumor cell lines using 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide and on the sea urchin egg development. Both compounds displayed cytotoxic activity against tumor cell lines, but only carnasol was able to inhibit the sea urchin egg cleavages.

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Year:  2004        PMID： 14964430

Source DB:  PubMed          Journal:  Pharmazie        ISSN： 0031-7144            Impact factor:   1.267


  6 in total

1.  Repeated-Doses Toxicity Study of the Essential Oil of Hyptis martiusii Benth. (Lamiaceae) in Swiss Mice.

Authors:  Germana Freire Rocha Caldas; Alice Valença Araújo; Giwellington Silva Albuquerque; Jacinto da Costa Silva-Neto; João Henrique Costa-Silva; Irwin Rose Alencar de Menezes; Ana Cristina Lima Leite; José Galberto Martins da Costa; Almir Gonçalves Wanderley
Journal:  Evid Based Complement Alternat Med       Date:  2013-09-10       Impact factor: 2.629

2.  Gastroprotective and ulcer healing effects of essential oil of Hyptis martiusii Benth. (Lamiaceae).

Authors:  Germana Freire Rocha Caldas; Alisson Rodrigo da Silva Oliveira; Alice Valença Araújo; Dafne Carolina Alves Quixabeira; Jacinto da Costa Silva-Neto; João Henrique Costa-Silva; Irwin Rose Alencar de Menezes; Fabiano Ferreira; Ana Cristina Lima Leite; José Galberto Martins da Costa; Almir Gonçalves Wanderley
Journal:  PLoS One       Date:  2014-01-15       Impact factor: 3.240

3.  Chemical Composition, Modulatory Bacterial Resistance and Antimicrobial Activity of Essential Oil the Hyptis martiusii Benth by Direct and Gaseous Contact.

Authors:  Allan Demetrius Leite de Oliveira; Fabiola Fernandes Galvao Rodrigue; Henrique Douglas Melo Coutinho; Jose Galberto Martins da Costa; Irwin Rose Alencar de Menezes
Journal:  Jundishapur J Nat Pharm Prod       Date:  2014-06-29

Review 4.  Essential Oils and Their Components as Modulators of Antibiotic Activity against Gram-Negative Bacteria.

Authors:  Petruta Aelenei; Anca Miron; Adriana Trifan; Alexandra Bujor; Elvira Gille; Ana Clara Aprotosoaie
Journal:  Medicines (Basel)       Date:  2016-07-28

Review 5.  Biologically Active Diterpenoids in the Clerodendrum Genus-A Review.

Authors:  Łukasz Kuźma; Jan Gomulski
Journal:  Int J Mol Sci       Date:  2022-09-20       Impact factor: 6.208

Review 6.  Subtribe Hyptidinae (Lamiaceae): A promising source of bioactive metabolites.

Authors:  Henrique Bridi; Gabriela de Carvalho Meirelles; Gilsane Lino von Poser
Journal:  J Ethnopharmacol       Date:  2020-08-05       Impact factor: 4.360
  6 in total

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