BACKGROUND: Rotavirus illness is associated with significant cause of morbidity and is a common cause of hospitalization worldwide. OBJECTIVE: This study was performed to assess the role of rotaviruses in children presenting with acute diarrhea in two main Children's Medical Centers and one general hospital in Tehran. STUDY DESIGN: Stool specimens from 704 children less than 5 years of age suffering from diarrhea were tested for the presence of rotaviruses by a monoclonal antibody-based enzyme immunoassay. A total of 176 fecal specimens collected from healthy children in similar age group were studied as controls. RESULTS: Rotavirus antigen was detected in 15.3% of patients. Infants between 6 and 12 months of age were most frequently affected. Rotavirus infection was significantly less frequent in breast-fed than among bottle-fed babies. Watery diarrhea was present in 68.5% of children. Detection rate was highest in the spring and lowest in summer. Rotavirus can be regarded as a major etiologic agent of acute diarrhea in infants and children up to 5-years-old in Iran, immunization at birth may protect the children before their first symptomatic infection.
BACKGROUND:Rotavirus illness is associated with significant cause of morbidity and is a common cause of hospitalization worldwide. OBJECTIVE: This study was performed to assess the role of rotaviruses in children presenting with acute diarrhea in two main Children's Medical Centers and one general hospital in Tehran. STUDY DESIGN: Stool specimens from 704 children less than 5 years of age suffering from diarrhea were tested for the presence of rotaviruses by a monoclonal antibody-based enzyme immunoassay. A total of 176 fecal specimens collected from healthy children in similar age group were studied as controls. RESULTS: Rotavirus antigen was detected in 15.3% of patients. Infants between 6 and 12 months of age were most frequently affected. Rotavirus infection was significantly less frequent in breast-fed than among bottle-fed babies. Watery diarrhea was present in 68.5% of children. Detection rate was highest in the spring and lowest in summer. Rotavirus can be regarded as a major etiologic agent of acute diarrhea in infants and children up to 5-years-old in Iran, immunization at birth may protect the children before their first symptomatic infection.
Authors: F Farahtaj; C I Gallimore; M Iturriza-Gomara; M Taremi; M R Zali; H Edalatkhah; A Fayaz; J J Gray Journal: Epidemiol Infect Date: 2006-11-17 Impact factor: 2.451
Authors: Ishtiaq Mannan; Yoonjoung Choi; Anastasia J Coutinho; Atique I Chowdhury; Syed Moshfiqur Rahman; Habib R Seraji; Sanwarul Bari; Rasheduzzaman Shah; Peter J Winch; Shams El Arifeen; Gary L Darmstadt; Abdullah H Baqui Journal: Int J Environ Res Public Health Date: 2011-08-22 Impact factor: 3.390
Authors: R Hamkar; Y Yahyapour; M Noroozi; K Nourijelyani; S Jalilvand; L Adibi; S Vaziri; Aa Poor-Babaei; A Pakfetrat; R Savad-Koohi Journal: Iran J Public Health Date: 2010-06-30 Impact factor: 1.429