Literature DB >> 1496277

[Rhabdomyolysis due to simvastin. Apropos of a case with review of the literature].

C Dromer1, C Vedrenne, T Billey, M Pages, B Fournié, A Fournié.   

Abstract

A new case of simvastatin-induced acute rhabdomyolysis with heart failure after initiation of treatment with fusidic acid is reported. In most reported instances, statin treatment was initially well tolerated with muscle toxicity developing only after addition of another drug. The mechanism of this muscle toxicity is unelucidated but involvement of a decrease in tissue Co enzyme Q is strongly suspected.

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Year:  1992        PMID: 1496277

Source DB:  PubMed          Journal:  Rev Rhum Mal Osteoartic        ISSN: 0035-2659


  4 in total

1.  Amyotrophic Lateral Sclerosis Associated with Statin Use: A Disproportionality Analysis of the FDA's Adverse Event Reporting System.

Authors:  Beatrice A Golomb; Abril Verden; Alexis K Messner; Hayley J Koslik; Keith B Hoffman
Journal:  Drug Saf       Date:  2018-04       Impact factor: 5.606

Review 2.  Simvastatin. A reappraisal of its pharmacology and therapeutic efficacy in hypercholesterolaemia.

Authors:  G L Plosker; D McTavish
Journal:  Drugs       Date:  1995-08       Impact factor: 9.546

Review 3.  Rhabdomyolysis after co-administration of a statin and fusidic acid: an analysis of the literature and of the WHO database of adverse drug reactions.

Authors:  Thomas Deljehier; Antoine Pariente; Ghada Miremont-Salamé; Françoise Haramburu; Linh Nguyen; Sébastien Rubin; Claire Rigothier; Hélène Théophile
Journal:  Br J Clin Pharmacol       Date:  2018-02-26       Impact factor: 4.335

Review 4.  Statin adverse effects : a review of the literature and evidence for a mitochondrial mechanism.

Authors:  Beatrice A Golomb; Marcella A Evans
Journal:  Am J Cardiovasc Drugs       Date:  2008       Impact factor: 3.571

  4 in total

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