Literature DB >> 14961204

Complications of thyroid surgery: analysis of a multicentric study on 14,934 patients operated on in Italy over 5 years.

Lodovico Rosato1, Nicola Avenia, Paolo Bernante, Maurizio De Palma, Giuseppe Gulino, Pier Giorgio Nasi, Maria Rosa Pelizzo, Luciano Pezzullo.   

Abstract

Complication rates associated with thyroid surgery can be evaluated only through analysis of case studies and follow-up data. This study covers postoperative data from 14,934 patients subjected to a follow-up of 5 years. Among them, 3130 (20.9%) underwent total lobectomy (TL), 9599 (64.3%) total thyroidectomy (TT), 1448 (9.7%) subtotal thyroidectomy with a monolateral remnant (MRST), and 757 (5.1%) subtotal thyroidectomy with bilateral remnants (BRST). A total of 6% of the patients had already been operated on. Persistent hypoparathyroidism occurred after 1.7% of all the operations, and temporary hypoparathyroidism was noted in 8.3%. Permanent palsy of the laryngeal recurrent nerve (LRN) occurred in 1.0% of patients, transient palsy in 2.0%, and diplegia in 0.4%. The superior laryngeal nerve was damaged in 3.7%; dysphagia occurred in 1.4% of cases, hemorrhage in 1.2%, and wound infection in 0.3%. No deaths were reported. A significant rate of LRN damage was noted, which has an important impact on the patient's social life. Hypoparathyroidism after total thyroidectomy is an important complication that can be successfully treated by therapy, although it is not always easily managed in special circumstances such as in young persons or pregnant women. The complications associated with thyroid surgery must be kept in mind so the surgeon can carefully evaluate the surgical and medical therapeutic options, have more precise surgical indications, and be able to give the patient adequate information.

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Year:  2004        PMID: 14961204     DOI: 10.1007/s00268-003-6903-1

Source DB:  PubMed          Journal:  World J Surg        ISSN: 0364-2313            Impact factor:   3.352


  19 in total

Review 1.  Surgeon's approach to the thyroid gland: surgical anatomy and the importance of technique.

Authors:  R D Bliss; P G Gauger; L W Delbridge
Journal:  World J Surg       Date:  2000-08       Impact factor: 3.352

Review 2.  Complications of thyroid surgery: how to avoid them, how to manage them, and observations on their possible effect on the whole patient.

Authors:  T Reeve; N W Thompson
Journal:  World J Surg       Date:  2000-08       Impact factor: 3.352

3.  Truncal ligation of the inferior thyroid arteries does not affect the incidence of hypocalcaemia after thyroidectomy.

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Journal:  Eur J Surg       Date:  2000-04

4.  [Prophylaxis of laryngeal nerve injuries in thyroid surgery].

Authors:  V O Bondarenko; A S Ermolov; R B Magomedov
Journal:  Khirurgiia (Mosk)       Date:  2001

5.  Intraoperative monitoring of the recurrent laryngeal nerve in 151 consecutive patients undergoing thyroid surgery.

Authors:  T M Hemmerling; J Schmidt; C Bosert; K E Jacobi; P Klein
Journal:  Anesth Analg       Date:  2001-08       Impact factor: 5.108

Review 6.  Identification of the external branch of the superior laryngeal nerve during thyroidectomy.

Authors:  C R Cernea; A R Ferraz; J Furlani; S Monteiro; S Nishio; F C Hojaij; A Dutra Júnior; L A Marques; P A Pontes; R G Bevilacqua
Journal:  Am J Surg       Date:  1992-12       Impact factor: 2.565

7.  The nonrecurrent inferior laryngeal nerve: review of 33 cases, including two on the left side.

Authors:  J F Henry; J Audiffret; A Denizot; M Plan
Journal:  Surgery       Date:  1988-12       Impact factor: 3.982

Review 8.  Hypocalcemia following thyroid surgery: incidence and prediction of outcome.

Authors:  F Pattou; F Combemale; S Fabre; B Carnaille; M Decoulx; J L Wemeau; A Racadot; C Proye
Journal:  World J Surg       Date:  1998-07       Impact factor: 3.352

9.  [Prevention of laryngeal nerve lesions in thyroid surgery].

Authors:  S Balanzoni; R Altini; L Pasi; F Fussi
Journal:  Minerva Chir       Date:  1994-04       Impact factor: 1.000

10.  Selective use of drains in thyroid surgery.

Authors:  A R Shaha; B M Jaffe
Journal:  J Surg Oncol       Date:  1993-04       Impact factor: 3.454

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  238 in total

1.  The factors related with postoperative complications in benign nodular thyroid surgery.

Authors:  Aysun Simsek Celik; Hasan Erdem; Deniz Guzey; Fatih Celebi; Atilla Celik; Selim Birol; Rafet Kaplan
Journal:  Indian J Surg       Date:  2010-11-18       Impact factor: 0.656

2.  Alternating from subtotal thyroid resection to total thyroidectomy in the treatment of Graves' disease prevents recurrences but increases the frequency of permanent hypoparathyroidism.

Authors:  Johannes Järhult; Per-Olof Andersson; Linda Duncker
Journal:  Langenbecks Arch Surg       Date:  2011-12-09       Impact factor: 3.445

3.  Short-stay hospitalisation for benign thyroid surgery: a prospective study.

Authors:  Fausto Fama'; Cecile Linard; Rosalia Patti; Miles G Berry; Maria Gioffre'-Florio; Arnaud Piquard; Olivier Saint-Marc
Journal:  Eur Arch Otorhinolaryngol       Date:  2012-06-13       Impact factor: 2.503

4.  Emergency endoscopic vocal cord lateralization as an alternative to tracheotomy for patients with bilateral abductor vocal cord paralysis.

Authors:  Cagatay Oysu; Asli Sahin-Yilmaz; Celil Uslu
Journal:  Eur Arch Otorhinolaryngol       Date:  2012-06-22       Impact factor: 2.503

5.  Recurrent laryngeal nerve and voice preservation: routine identification and appropriate assessment - two important steps in thyroid surgery.

Authors:  Ravindra Singh Mohil; Pragnesh Desai; Nitisha Narayan; Maheswar Sahoo; Dinesh Bhatnagar; V P Venkatachalam
Journal:  Ann R Coll Surg Engl       Date:  2010-08-19       Impact factor: 1.891

6.  [Bilateral vocal cord paresis after total thyroidectomy].

Authors:  H Dralle; J Neu; T J Musholt; C Nies
Journal:  Chirurg       Date:  2016-01       Impact factor: 0.955

7.  Radiofrequency ablation for thyroid nodules: which indications? The first Italian opinion statement.

Authors:  Roberto Garberoglio; Camillo Aliberti; Marialuisa Appetecchia; Marco Attard; Giuseppe Boccuzzi; Flavio Boraso; Giorgio Borretta; Giuseppe Caruso; Maurilio Deandrea; Milena Freddi; Gabriella Gallone; Giovanni Gandini; Guido Gasparri; Carlo Gazzera; Ezio Ghigo; Maurizio Grosso; Paolo Limone; Mauro Maccario; Luigi Mansi; Alberto Mormile; Pier Giorgio Nasi; Fabio Orlandi; Donatella Pacchioni; Claudio Maurizio Pacella; Nicola Palestini; Enrico Papini; Maria Rosa Pelizzo; Andrea Piotto; Teresa Rago; Fabrizio Riganti; Lodovico Rosato; Ruth Rossetto; Antonio Scarmozzino; Stefano Spiezia; Ornella Testori; Roberto Valcavi; Andrea Veltri; Paolo Vitti; Matteo Zingrillo
Journal:  J Ultrasound       Date:  2015-06-19

8.  Role of sentinel node in differentiated thyroid cancer: a prospective study comparing patent blue injection technique, lymphoscintigraphy and the combined technique.

Authors:  R Gelmini; M Campanelli; F Cabry; A Franceschetto; G Ceresini; L Ruffini; A Zaccaroni; P Del Rio
Journal:  J Endocrinol Invest       Date:  2017-08-31       Impact factor: 4.256

9.  The timing of parathyroid hormone measurement defines the cut-off values to accurately predict postoperative hypocalcemia: a prospective study.

Authors:  Eduardo Bardou Yunes Filho; Rafael Vaz Machry; Rodrigo Mesquita; Rafael Selbach Scheffel; Ana Luiza Maia
Journal:  Endocrine       Date:  2018-05-02       Impact factor: 3.633

Review 10.  Efficacy and safety of cooled and uncooled microwave ablation for the treatment of benign thyroid nodules: a systematic review and meta-analysis.

Authors:  Bo-Wen Zheng; Jin-Fen Wang; Jin-Xiu Ju; Tao Wu; Ge Tong; Jie Ren
Journal:  Endocrine       Date:  2018-11       Impact factor: 3.633

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