Literature DB >> 1493923

The distribution of immunoreactive interferon-gamma-containing cells in normal human tissues.

F Brett1, A Mowat, M A Farquharson, M McGill, C Hind, J Richmond, D Murray, N U Khan, A K Foulis.   

Abstract

An immunohistochemical technique has been used to study the distribution of lymphocytes expressing interferon-gamma in normal adult tissues. The greatest concentrations of these cells were seen in mucosal sites exposed to a resident microflora. It is proposed that such organisms, by eliciting immune responses, provide the stimulus for the production of 'physiological' interferon-gamma. This in turn may act to preserve the 'tone' or readiness of the immune system.

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Year:  1992        PMID： 1493923      PMCID： PMC1421654     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  16 in total

1.  The distribution of immunoreactive interferon-alpha in normal human tissues.

Authors:  N U Khan; K A Pulford; M A Farquharson; A Howatson; C Stewart; R Jackson; A M McNicol; A K Foulis
Journal:  Immunology       Date:  1989-02       Impact factor: 7.397

2.  Lymphokine dependence of in vivo expression of MHC class II antigens by endothelium.

Authors:  G Groenewegen; W A Buurman; C J van der Linden
Journal:  Nature       Date:  1985 Jul 25-31       Impact factor: 49.962

Review 3.  Natural killer cells.

Authors:  J C Roder; K Karre; R Kiessling
Journal:  Prog Allergy       Date:  1981

4.  The distribution of immunoreactive interferon-alpha in formalin-fixed paraffin-embedded normal human foetal and infant tissues.

Authors:  N U Khan; A Gibson; A K Foulis
Journal:  Immunology       Date:  1990-10       Impact factor: 7.397

5.  Intestinal immune responses in humans. Oral cholera vaccination induces strong intestinal antibody responses and interferon-gamma production and evokes local immunological memory.

Authors:  M Quiding; I Nordström; A Kilander; G Andersson; L A Hanson; J Holmgren; C Czerkinsky
Journal:  J Clin Invest       Date:  1991-07       Impact factor: 14.808

6.  Detection of Epstein-Barr virus antigens and DNA in major and minor salivary glands using immunocytochemistry and polymerase chain reaction: possible relationship with Sjogren's syndrome.

Authors:  E M Deacon; J B Matthews; A J Potts; J Hamburger; I S Bevan; L S Young
Journal:  J Pathol       Date:  1991-04       Impact factor: 7.996

7.  Development of delayed hypersensitivity in gnotobiotic mice.

Authors:  F M Collins; P B Carter
Journal:  Int Arch Allergy Appl Immunol       Date:  1980

8.  Spatial correlation between thyroid epithelial cells expressing class II MHC molecules and interferon-gamma-containing lymphocytes in human thyroid autoimmune disease.

Authors:  F Hamilton; M Black; M A Farquharson; C Stewart; A K Foulis
Journal:  Clin Exp Immunol       Date:  1991-01       Impact factor: 4.330

9.  Induction of various HLA class II molecules in a human colonic adenocarcinoma cell line.

Authors:  L M Sollid; G Gaudernack; G Markussen; D Kvale; P Brandtzaeg; E Thorsby
Journal:  Scand J Immunol       Date:  1987-02       Impact factor: 3.487

10.  Insulitis in type 1 (insulin-dependent) diabetes mellitus in man--macrophages, lymphocytes, and interferon-gamma containing cells.

Authors:  A K Foulis; M McGill; M A Farquharson
Journal:  J Pathol       Date:  1991-10       Impact factor: 7.996
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  2 in total

1.  Interferon-gamma receptor-deficient mice exhibit impaired gut mucosal immune responses but intact oral tolerance.

Authors:  M Kjerrulf; D Grdic; L Ekman; K Schön; M Vajdy; N Y Lycke
Journal:  Immunology       Date:  1997-09       Impact factor: 7.397

2.  Immune activation during infancy in healthy humans.

Authors:  A G Cummins; B A Eglinton; A Gonzalez; D M Roberton
Journal:  J Clin Immunol       Date:  1994-03       Impact factor: 8.317
  2 in total

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